Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5646444 | 0.91 | MAP3K5 (0.39) | MAPTALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL29565421 | 0.85 | MAPT (0.43) | DGAT1SOAT1MAPTALDH1A1MEN1 | |
| SCHEMBL4598178 | 0.85 | MAPT (0.43) | DGAT1SOAT1MAPTALDH1A1MEN1 | |
| SCHEMBL5646123 | 0.83 | MAP3K5 (0.41) | MAPTALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL3830804 | 0.80 | ALDH1A1 (0.42) | DGAT1SOAT1MAPTALDH1A1MEN1 | |
| SCHEMBL3822262 | 0.79 | ALDH1A1 (0.40) | DGAT1SOAT1MAPTALDH1A1MEN1 | |
| SCHEMBL26808258 | 0.76 | KMT2A (0.33) | MAPTALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL8919915 | 0.76 | MEN1 (0.38) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL5650561 | 0.76 | TP53 (0.37) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL26808079 | 0.76 | KDM4E (0.33) | MAPTALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166357-B2 | Photochromic articles that activate behind ultraviolet radiation blocking transparencies and methods for preparation | TRANSITIONS OPTICAL, INC. (US) | 2007-01-23 | — | — | US | claimed |
| US-20040185268-A1 | Photochromic articles that activate behind ultraviolet radiation blocking transparencies and methods for preparation | TRANSITIONS OPTICAL LIMITED (IE) | 2004-09-23 | — | — | US | claimed |
| US-5891368-A | PHOTOCHROMIC COMPOUNDS AND COATINGS WITH COMPOUNDS | PPG INDUSTRIES, INC. (US) | 1999-04-06 | — | — | US | claimed |
| US-7166357-B2 | Photochromic articles that activate behind ultraviolet radiation blocking transparencies and methods for preparation | TRANSITIONS OPTICAL, INC. (US) | 2007-01-23 | — | — | US | disclosed |
| US-20040185268-A1 | Photochromic articles that activate behind ultraviolet radiation blocking transparencies and methods for preparation | TRANSITIONS OPTICAL LIMITED (IE) | 2004-09-23 | — | — | US | disclosed |
| US-5891368-A | PHOTOCHROMIC COMPOUNDS AND COATINGS WITH COMPOUNDS | PPG INDUSTRIES, INC. (US) | 1999-04-06 | — | — | US | disclosed |