Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Triclobisonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triclobisonium SCHEMBL15552713 | 0.99 | — | — | |
| Triclobisonium SCHEMBL29385191 | 0.99 | — | — | |
| Hydrochloric Acid SCHEMBL11792589 | 0.84 | — | — | |
| Iodide SCHEMBL11791559 | 0.81 | — | — | |
| Bromide SCHEMBL11791722 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL15552335 | 0.80 | — | — | |
| Iodide SCHEMBL11793590 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL14861567 | 0.77 | — | — | |
| SCHEMBL7941755 | 0.76 | L3MBTL1 (0.31) | — | |
| SCHEMBL7933160 | 0.76 | L3MBTL1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 310 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3263145-B1 | ANTIMICROBIAL COMPOSITIONS AND METHODS FOR LOCKING CATHETERS | BECTON DICKINSON CO (US) | 2021-01-20 | — | — | EP | claimed |
| EP-2766336-B1 | PROCESS FOR PREPARING ALKOXY ARYL ESTER | SAUDI BASIC IND CORP (SA) | 2018-08-29 | — | — | EP | claimed |
| US-9872941-B2 | Antimicrobial compositions and methods for locking catheters | BECTON, DICKINSON AND COMPANY (US) | 2018-01-23 | — | — | US | claimed |
| EP-3263145-A1 | ANTIMICROBIAL COMPOSITIONS AND METHODS FOR LOCKING CATHETERS | Becton, Dickinson and Company (US) | 2018-01-03 | — | — | EP | claimed |
| EP-1998825-B1 | ANTIMICROBIAL COMPOSITIONS AND METHODS FOR LOCKING CATHETERS | BECTON DICKINSON CO (US) | 2017-10-18 | — | — | EP | claimed |
| US-20170216493-A1 | Antimicrobial Compositions and Methods for Locking Catheters | BECTON, DICKINSON AND COMPANY | 2017-08-03 | — | — | US | claimed |
| US-9649411-B2 | Antimicrobial compositions and methods for locking catheters | BECTON, DICKINSON AND COMPANY (US) | 2017-05-16 | — | — | US | claimed |
| US-20160213818-A1 | Antimicrobial Compositions and Methods for Locking Catheters | BECTON, DICKINSON AND COMPANY | 2016-07-28 | — | — | US | claimed |
| US-9187401-B2 | Process for preparing alkoxy aryl ester | SAUDI BASIC INDUSTRIES CORPORATION (SA) | 2015-11-17 | — | — | US | claimed |
| US-20140275604-A1 | PROCESS FOR PREPARING ALKOXY ARYL ESTER | SAUDI BASIC INDUSTRIES CORPORATION (SA) | 2014-09-18 | — | — | US | claimed |
| JP-2009528360-A | — | — | 2009-08-06 | — | — | JP | claimed |
| CN-101426539-A | Antimicrobial compositions and methods of locking catheters | BECTON DICKINSON CO (US) | 2009-05-06 | — | — | CN | claimed |
| EP-1998825-A2 | ANTIMICROBIAL COMPOSITIONS AND METHODS FOR LOCKING CATHETERS | Becton, Dickinson and Company, Wagner, Jaconda (US) | 2008-12-10 | — | — | EP | claimed |
| WO-2007100776-A2 | ANTIMICROBIAL COMPOSITIONS AND METHODS FOR LOCKING CATHETERS | BECTON, DICKINSON AND COMPANY (US) | 2007-09-07 | — | — | WO | claimed |
| US-20070202177-A1 | Antimicrobial Compositions and Methods for Locking Catheters | BECTON, DICKINSON AND COMPANY (US) | 2007-08-30 | — | — | US | claimed |
| CN-1544596-A | Male sexual function lotion and preparing process thereof | 裴景文 | 2004-11-10 | — | — | CN | claimed |
| WO-1994027436-A1 | PRESERVATIVE SYSTEMS WITH ENHANCED ANTIMICROBIAL ACTIVITY | DECICCO BENEDICT T (US) | 1994-12-08 | — | — | WO | claimed |
| US-5357636-A | Flexible protective medical gloves and methods for their use | DRESDNER JR KARL P (US) | 1994-10-25 | — | — | US | claimed |
| US-4394381-A | QUARTERNARY AMMONIUM SURFACTANT BACTERICIDE | GEORGE F. AND IRENE SHERRILL 1978 TRUST NO. 1 (US) | 1983-07-19 | — | — | US | claimed |
| US-4262007-A | TOPICAL APPLICATION | Sherrill, George F. | 1981-04-14 | — | — | US | claimed |