Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | HTR6 | P50406 | 2/20 | 0.62 |
| ▸ | IL1RN | P18510 | 1/20 | 0.61 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.61 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 4/20 | 0.57 |
| ▸ | CA9 | Q16790 | 4/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.54 |
| ▸ | LIMK2 | P53671 | 2/20 | 0.52 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28692275 | 0.86 | KMT2A (0.67) | KMT2AMEN1ALDH1A1PKMHTR6 | |
| SCHEMBL11055810 | 0.83 | POLB (0.52) | KMT2AMEN1ALDH1A1PKMHTR6 | |
| SCHEMBL9231538 | 0.83 | KMT2A (0.62) | KMT2AMEN1ALDH1A1PKMHTR6 | |
| SCHEMBL10960830 | 0.83 | TDP1 (0.52) | ALDH1A1HTR6KEAP1CA12CA9 | |
| Water SCHEMBL27650777 | 0.80 | FFAR1 (0.72) | KMT2AMEN1ALDH1A1PKMHTR6 | |
| SCHEMBL10088132 | 0.79 | KMT2A (0.67) | KMT2AMEN1ALDH1A1PKMHTR6 | |
| SCHEMBL12058761 | 0.79 | UCHL1 (0.75) | KMT2AMEN1ALDH1A1PKMHTR6 | |
| SCHEMBL7610798 | 0.79 | HTR6 (0.73) | KMT2AMEN1ALDH1A1PKMHTR6 | |
| SCHEMBL10453153 | 0.79 | KMT2A (0.67) | KMT2AMEN1ALDH1A1PKMHTR6 | |
| SCHEMBL8643787 | 0.78 | PRMT1 (0.68) | KMT2AMEN1ALDH1A1PKMHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070049620-A1 | Cyclic tertiary amine compound | SANKYO COMPANY, LIMITED (JP) | 2007-03-01 | — | — | US | disclosed |
| EP-1632488-A1 | CYCLIC TERTIARY AMINE COMPOUND | Sankyo Company, Limited (JP) | 2006-03-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070049620-A1 | Cyclic tertiary amine compound | MYD88, IL5, BRD4 | KMT2A 2948/4885MEN1 3030/4885ALDH1A1 1438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.