Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5651599 | 0.87 | KCNH2 (0.46) | KCNH2SLC2A1 | |
| SCHEMBL3687758 | 0.85 | CNR2 (0.33) | CYP2D6ADRA1A | |
| SCHEMBL5254666 | 0.81 | KCNH2 (0.57) | KCNH2SLC2A1MCHR1 | |
| SCHEMBL5319422 | 0.77 | KCNH2 (0.35) | KCNH2SLC2A1 | |
| SCHEMBL5652075 | 0.73 | CCR8 (0.45) | KCNH2SLC2A1CYP2D6ALDH1A1HSD17B10 | |
| SCHEMBL3691027 | 0.72 | CYP2D6 (0.33) | KCNH2CYP2D6OPRM1ADRA1A | |
| SCHEMBL5651625 | 0.72 | KCNH2 (0.35) | KCNH2SLC2A1CYP2D6ALDH1A1HSD17B10 | |
| SCHEMBL5653940 | 0.72 | KCNH2 (0.39) | KCNH2SLC2A1CYP2D6ALDH1A1HSD17B10 | |
| SCHEMBL5648717 | 0.71 | KCNH2 (0.47) | KCNH2SLC2A1 | |
| SCHEMBL16566559 | 0.68 | ALDH1A1 (0.37) | KCNH2ALDH1A1HSD17B10KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223776-B2 | Compounds with anti-bacterial activity | MORPHOCHEM AG (DE) | 2007-05-29 | — | — | US | disclosed |
| US-20060040949-A1 | Novel compounds with antibacterial activity | MORPHOCHEM AG | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060040949-A1 | Novel compounds with antibacterial activity | MRPL21, Q6ZSR9, MRPL19 | KCNH2 2411/4885SLC2A1 4070/4885CYP2D6 1401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.