Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.57 |
| ▸ | NQO2 | P16083 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL406429 | 0.81 | CA2 (0.54) | HPGDTDP1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL8794788 | 0.79 | HPGD (0.64) | MTNR1ANQO2HPGDTDP1CYP1A2 | |
| SCHEMBL3047898 | 0.76 | CYP1A2 (0.62) | MTNR1ANQO2TDP1CYP1A2CYP2C19 | |
| SCHEMBL2255099 | 0.76 | MTNR1A (0.62) | MTNR1ANQO2HPGDTDP1CYP1A2 | |
| SCHEMBL3637276 | 0.76 | MTNR1A (0.57) | MTNR1ANQO2HPGDTDP1CYP1A2 | |
| SCHEMBL606293 | 0.76 | MTNR1A (0.63) | MTNR1ANQO2HPGDCYP1A2CYP2C19 | |
| SCHEMBL29061337 | 0.76 | MTNR1A (0.57) | MTNR1ANQO2HPGDTDP1CYP1A2 | |
| SCHEMBL143457 | 0.76 | MTNR1A (0.49) | MTNR1ANQO2HPGDTDP1CYP1A2 | |
| SCHEMBL19553634 | 0.76 | MTNR1A (0.62) | MTNR1ANQO2HPGDTDP1CYP1A2 | |
| SCHEMBL30736517 | 0.75 | MTNR1A (0.57) | MTNR1ANQO2HPGDTDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5140009-A | Stable against proteolytic enzymes; anticarcinogenic agents; urogenital disorders | TAP PHARMACEUTICALS, INC. (US) | 1992-08-18 | — | — | US | claimed |
| EP-0417454-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1991-03-20 | — | — | EP | claimed |
| US-20070049620-A1 | Cyclic tertiary amine compound | SANKYO COMPANY, LIMITED (JP) | 2007-03-01 | — | — | US | disclosed |
| EP-1632488-A1 | CYCLIC TERTIARY AMINE COMPOUND | Sankyo Company, Limited (JP) | 2006-03-08 | — | — | EP | disclosed |
| EP-0671975-B2 | CHIRAL ADSORBENTS AND PREPARATION THEREOF AS WELL AS COMPOUNDS ON WHICH THE ADSORBENTS ARE BASED AND PREPARATION OF THESE COMPOUNDS | EKA CHEMICALS AB (SE) | 2002-07-03 | — | — | EP | disclosed |
| US-6333426-B1 | CHIRAL STATIONARY PHASES BASED ON NETWORK POLYMERS OF TARTARIC ACID DERIVATIVES EXHIBIT GENERAL ENANTIOSELECTIVITY FOR MOST TYPES OF PHARMACEUTICAL SUBSTANCES | EKA NOBEL AB (SE) | 2001-12-25 | — | — | US | disclosed |
| US-6277782-B1 | POLYMER BONDED TO CARRIER | EKA NOBEL AB (SE) | 2001-08-21 | — | — | US | disclosed |
| EP-0671975-B1 | CHIRAL ADSORBENTS AND PREPARATION THEREOF AS WELL AS COMPOUNDS ON WHICH THE ADSORBENTS ARE BASED AND PREPARATION OF THESE COMPOUNDS | EKA CHEMICALS AB (SE) | 1998-07-22 | — | — | EP | disclosed |
| EP-0671975-A1 | CHIRAL ADSORBENTS AND PREPARATION THEREOF AS WELL AS COMPOUNDS ON WHICH THE ADSORBENTS ARE BASED AND PREPARATION OF THESE COMPOUNDS | Eka Chemicals AB (SE) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994012275-A1 | CHIRAL ADSORBENTS AND PREPARATION THEREOF AS WELL AS COMPOUNDS ON WHICH THE ADSORBENTS ARE BASED AND PREPARATION OF THESE COMPOUNDS | EKA NOBEL AB (SE) | 1994-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070049620-A1 | Cyclic tertiary amine compound | MYD88, IL5, BRD4 | MTNR1A 2187/4885NQO2 882/4885HPGD 1549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.