Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5644668 | 0.92 | PTGS2 (0.76) | PTGS2PTGS1 | |
| SCHEMBL6092117 | 0.86 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL16707183 | 0.86 | PTGS2 (0.70) | PTGS2PTGS1 | |
| SCHEMBL5643533 | 0.85 | PTGS2 (0.58) | PTGS2PTGS1 | |
| SCHEMBL5647418 | 0.84 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL6093508 | 0.84 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL5643667 | 0.84 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL20646388 | 0.84 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL5768918 | 0.84 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL27918704 | 0.84 | PTGS2 (0.57) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7259266-B2 | Benzopyran compounds useful for treating inflammatory conditions | PHARMACIA CORPORATION (US) | 2007-08-21 | — | — | US | disclosed |
| US-20050148627-A1 | Benzopyran compounds for use in the treatment and prevention of inflammation related conditions | CARTER JEFFERY (US) | 2005-07-07 | — | — | US | disclosed |
| US-20050148777-A1 | Benzopyran compounds useful for treating inflammatory conditions | CARTER JEFFERY (US) | 2005-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148777-A1 | Benzopyran compounds useful for treating inflammatory conditions | PTGES2, PTGER2, PTGS2 | PTGS2 3/4885PTGS1 6/4885 |
| US-20050148627-A1 | Benzopyran compounds for use in the treatment and prevention of inflammation related conditions | PTGES2, PTGER2, PTGES | PTGS2 4/4885PTGS1 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.