Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 1/20 | 0.49 |
| ▸ | APLNR | P35414 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | PRKCG | P05129 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.44 |
| ▸ | BRSK1 | Q8TDC3 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 6/20 | 0.43 |
| ▸ | MGAM | O43451 | 4/20 | 0.43 |
| ▸ | SI | P14410 | 4/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5650407 | 0.92 | APLNR (0.47) | HPSEAPLNRPRKD3PRKCGPIM1 | |
| SCHEMBL5650424 | 0.87 | HPSE (0.50) | HPSEAPLNRGAAMGAMSI | |
| SCHEMBL5651370 | 0.87 | HPSE (0.51) | HPSEAPLNRPRKD3PRKCGPIM1 | |
| SCHEMBL5649826 | 0.86 | GAA (0.43) | HPSETSHRGAATP53KDM4E | |
| SCHEMBL5654376 | 0.86 | TSHR (0.43) | TSHRGAATP53KDM4EHSD17B10 | |
| SCHEMBL5651004 | 0.86 | TP53 (0.44) | TSHRGAATP53KDM4EHSD17B10 | |
| SCHEMBL5649050 | 0.85 | HPSE (0.53) | HPSEPRKD3PRKCGPIM1GSK3A | |
| SCHEMBL5651923 | 0.85 | PRKD3 (0.45) | APLNRPRKD3PRKCGPIM1GSK3A | |
| SCHEMBL5650314 | 0.83 | HDAC6 (0.47) | TSHRGAATP53KDM4EHSD17B10 | |
| SCHEMBL5651963 | 0.82 | HTT (0.47) | HPSETSHRGAATP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220769-B2 | Azolylbenzamides and analogues and their use for treating osteoporosis | NIKEM RESEARCH S.R.L. (IT) | 2007-05-22 | — | — | US | disclosed |
| US-20050038095-A1 | Azolylbenzamides and analogues and their use for treating osteoporosis | 3-V BIOSCIENCES, INC. | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038095-A1 | Azolylbenzamides and analogues and their use for treating osteoporosis | NR0B2, NR0B1, NCOR1 | HPSE 3728/4885APLNR 435/4885PRKD3 1980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.