Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | S100B | P04271 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536599 | 0.89 | L3MBTL1 (0.56) | ALDH1A1GAAL3MBTL1HSD17B10TDP1 | |
| SCHEMBL11557943 | 0.89 | L3MBTL1 (0.50) | ALDH1A1GAAL3MBTL1HSD17B10TDP1 | |
| Hydrochloric Acid SCHEMBL9009886 | 0.87 | L3MBTL1 (0.54) | ALDH1A1GAAL3MBTL1HSD17B10TDP1 | |
| SCHEMBL11297214 | 0.83 | L3MBTL1 (0.50) | ALDH1A1GAAL3MBTL1HSD17B10TDP1 | |
| SCHEMBL926329 | 0.81 | L3MBTL1 (0.67) | ALDH1A1GAAL3MBTL1HSD17B10TDP1 | |
| SCHEMBL8837252 | 0.78 | L3MBTL1 (0.44) | ALDH1A1GAAL3MBTL1HSD17B10TDP1 | |
| SCHEMBL6371307 | 0.78 | GAA (0.68) | ALDH1A1GAAL3MBTL1HSD17B10TDP1 | |
| SCHEMBL30949891 | 0.78 | GAA (0.50) | ALDH1A1GAAL3MBTL1HSD17B10TDP1 | |
| SCHEMBL31716014 | 0.77 | ALDH1A1 (0.46) | ALDH1A1GAAL3MBTL1HSD17B10TDP1 | |
| SCHEMBL11376859 | 0.77 | L3MBTL1 (0.46) | ALDH1A1GAAL3MBTL1HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070299092-A1 | Quinone Substituted Quinazoline and Quinoline Kinase Inhibitors | WYETH (US) | 2007-12-27 | — | — | US | disclosed |
| WO-2005115145-A2 | QUINONE SUBSTITUTED QUINAZOLINE AND QUINOLINE KINASE INHIBITORS | WYETH (US) | 2005-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299092-A1 | Quinone Substituted Quinazoline and Quinoline Kinase Inhibitors | KDR, FLT1, FLT4 | ALDH1A1 530/4885GAA 2151/4885L3MBTL1 3552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.