Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 4/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709073 | 0.90 | MEN1 (0.42) | PRMT1PTPN1MEN1NPC1USP2 | |
| SCHEMBL1709067 | 0.88 | PTPN1 (0.39) | PRMT1PTPN1DPP8DPP9MEN1 | |
| SCHEMBL5651416 | 0.83 | PRMT1 (0.44) | PRMT1PTPN1DPP8DPP9MEN1 | |
| SCHEMBL5651412 | 0.83 | PRMT1 (0.44) | PRMT1PTPN1DPP8DPP9MEN1 | |
| SCHEMBL13070158 | 0.83 | PRMT1 (0.44) | PRMT1PTPN1DPP8DPP9MEN1 | |
| SCHEMBL5653734 | 0.79 | ADORA1 (0.41) | PRMT1PTPN1DPP8DPP9MEN1 | |
| SCHEMBL5653731 | 0.79 | ADORA1 (0.41) | PRMT1PTPN1DPP8DPP9MEN1 | |
| SCHEMBL1709068 | 0.79 | MEN1 (0.38) | PRMT1PTPN1MEN1NPC1USP2 | |
| SCHEMBL1709079 | 0.78 | PRMT1 (0.33) | PRMT1MEN1NPC1USP2S1PR2 | |
| SCHEMBL13050799 | 0.78 | PRMT1 (0.40) | PRMT1PTPN1DPP8DPP9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120088262-A1 | CYANINE COMPOUNDS, CONJUGATES AND METHOD OF USE | MILLIPORE CORPORATION (US) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088262-A1 | CYANINE COMPOUNDS, CONJUGATES AND METHOD OF USE | CASP7, MCL1, CARS1 | PRMT1 684/4885PTPN1 3862/4885DPP8 2596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.