Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | CTSK | P43235 | 4/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28298605 | 0.94 | TSHR (0.44) | TSHRHPGDMETAP1THRBCTSK | |
| SCHEMBL13435134 | 0.88 | TSHR (0.38) | TSHRHPGDCTSKCTSLCTSB | |
| SCHEMBL1355183 | 0.82 | TSHR (0.35) | TSHRHPGDTHRB | |
| SCHEMBL8151346 | 0.81 | TSHR (0.44) | TSHRHPGDMETAP1THRBCTSK | |
| SCHEMBL27349784 | 0.81 | TSHR (0.41) | TSHRHPGDMETAP1THRBCTSK | |
| SCHEMBL14218962 | 0.80 | THRB (0.41) | TSHRTHRBTHRALMNAALDH1A1 | |
| SCHEMBL13296349 | 0.80 | IDO1 (0.37) | TSHRHPGDTHRBLMNAALDH1A1 | |
| SCHEMBL13348377 | 0.79 | TSHR (0.36) | TSHRHPGDLMNAALDH1A1CYP3A4 | |
| SCHEMBL9578994 | 0.79 | TSHR (0.54) | TSHRHPGDTHRBCTSKTHRA | |
| SCHEMBL13348380 | 0.79 | TSHR (0.34) | TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120035323-A1 | POLYOLEFIN/POLYLACTIC ACID BLENDS | ARKEMA INC. (US) | 2012-02-09 | — | — | US | claimed |