Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 8/20 | 0.41 |
| ▸ | THRA | P10827 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SCN1A | P35498 | 2/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14218973 | 0.94 | THRB (0.39) | THRBTHRAALDH1A1HTTMEN1 | |
| SCHEMBL14218972 | 0.89 | SCN1A (0.39) | THRBTHRAALDH1A1HTTMEN1 | |
| SCHEMBL565179 | 0.80 | TSHR (0.46) | THRBTHRAALDH1A1TSHRLMNA | |
| SCHEMBL28298605 | 0.75 | TSHR (0.44) | THRBALDH1A1TSHR | |
| SCHEMBL14218989 | 0.71 | THRB (0.43) | THRBTHRAALDH1A1MEN1KMT2A | |
| SCHEMBL13296349 | 0.71 | IDO1 (0.37) | THRBALDH1A1MAPTTSHRLMNA | |
| SCHEMBL13435134 | 0.71 | TSHR (0.38) | MAPTTSHR | |
| SCHEMBL14192523 | 0.70 | SCN1A (0.44) | THRBTHRAALDH1A1HTTMEN1 | |
| SCHEMBL19499024 | 0.69 | THRB (0.38) | THRBTHRAALDH1A1HTTKMT2A | |
| SCHEMBL13348377 | 0.68 | TSHR (0.36) | ALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |