Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.55 |
| ▸ | PTPRF | P10586 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
| ▸ | IKBKB | O14920 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | BTK | Q06187 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14367853 | 0.84 | MKNK1 (0.55) | PTPN1CYP1A2CYP3A4CYP2C9ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5653571 | 0.82 | MKNK1 (0.54) | PTPN1CYP1A2CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL13118033 | 0.80 | MAPT (0.39) | PTPN1PTPRFMAPTMEN1KMT2A | |
| SCHEMBL13004629 | 0.79 | XDH (0.46) | PTPN1PTPRFMAPTMEN1KMT2A | |
| SCHEMBL3585269 | 0.78 | KDM4E (0.56) | PTPN1PTPRFMAPTMEN1KMT2A | |
| SCHEMBL2158793 | 0.78 | PTPRF (0.55) | PTPN1PTPRFMAPTMEN1KMT2A | |
| SCHEMBL2044907 | 0.78 | IKBKB (0.77) | PTPN1PTPRFMAPTMEN1KMT2A | |
| SCHEMBL17201623 | 0.77 | ADORA1 (0.39) | PTPN1PTPRFMAPTMEN1KMT2A | |
| SCHEMBL2158576 | 0.76 | IKBKB (0.75) | PTPN1PTPRFMAPTMEN1KMT2A | |
| SCHEMBL2248681 | 0.75 | IKBKB (0.60) | PTPN1PTPRFMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070270458-A1 | Nicotinic Acetylcholine Receptor Ligands | ASTRAZENECA AB (SE) | 2007-11-22 | — | — | US | disclosed |
| CN-1914201-A | Nicotinic acetylcholine receptor ligands | ASTRAZENECA AB (SE) | 2007-02-14 | — | — | CN | disclosed |
| EP-1699786-A1 | NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | AstraZeneca AB (SE) | 2006-09-13 | — | — | EP | disclosed |
| WO-2005061494-A1 | NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | ASTRAZENECA AB (SE) | 2005-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070270458-A1 | Nicotinic Acetylcholine Receptor Ligands | CHRNA2, CHRNA1, CHRNA6 | PTPN1 2063/4885PTPRF 2718/4885MAPT 1079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.