Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | EP300 | Q09472 | 2/20 | 0.55 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30503944 | 0.81 | SMN1; SMN2 (0.61) | IDO1EP300KAT8ALDH1A1SMN1; SMN2 | |
| SCHEMBL3670609 | 0.81 | SMN1; SMN2 (0.61) | IDO1EP300KAT8ALDH1A1SMN1; SMN2 | |
| SCHEMBL17787244 | 0.78 | IDO1 (0.55) | IDO1EP300KAT8ALDH1A1KDM4E | |
| SCHEMBL29741516 | 0.78 | KDM4E (0.56) | IDO1EP300KAT8ALDH1A1SMN1; SMN2 | |
| SCHEMBL3760438 | 0.78 | KDM4E (0.56) | IDO1EP300KAT8ALDH1A1SMN1; SMN2 | |
| SCHEMBL21830347 | 0.76 | ALDH1A1 (0.54) | IDO1EP300KAT8ALDH1A1SMN1; SMN2 | |
| SCHEMBL30678878 | 0.76 | SMN1; SMN2 (0.54) | IDO1EP300KAT8ALDH1A1SMN1; SMN2 | |
| SCHEMBL17765084 | 0.76 | EP300 (0.55) | IDO1EP300KAT8ALDH1A1SMN1; SMN2 | |
| SCHEMBL3734274 | 0.76 | SMN1; SMN2 (0.54) | IDO1EP300KAT8ALDH1A1SMN1; SMN2 | |
| SCHEMBL3747262 | 0.76 | SMN1; SMN2 (0.54) | IDO1EP300KAT8ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070299092-A1 | Quinone Substituted Quinazoline and Quinoline Kinase Inhibitors | WYETH (US) | 2007-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299092-A1 | Quinone Substituted Quinazoline and Quinoline Kinase Inhibitors | KDR, FLT1, FLT4 | IDO1 1321/4885EP300 3216/4885KAT8 4362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.