Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 9/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4793196 | 0.92 | KDR (0.42) | PDE10AKMT2AALDH1A1PDGFRBMAP3K5 | |
| SCHEMBL4983355 | 0.84 | PDE10A (0.44) | PDE10AALDH1A1PDGFRBMAP3K5 | |
| SCHEMBL4975690 | 0.82 | PDE10A (0.46) | PDE10AKMT2AALDH1A1PDGFRBMAP3K5 | |
| SCHEMBL4794767 | 0.79 | PDE10A (0.41) | PDE10APDGFRB | |
| SCHEMBL9025523 | 0.75 | RORC (0.56) | KMT2AALDH1A1RORCMEN1PKM | |
| SCHEMBL5653371 | 0.75 | PDE10A (0.47) | PDE10AKMT2AALDH1A1PDGFRBMEN1 | |
| SCHEMBL4778828 | 0.72 | PDE10A (0.43) | PDE10AKMT2AALDH1A1PDGFRBMEN1 | |
| SCHEMBL5302614 | 0.70 | PDE10A (0.47) | PDE10AKMT2AALDH1A1PDGFRBMEN1 | |
| SCHEMBL1600115 | 0.69 | KMT2A (0.47) | KMT2AALDH1A1RORCMEN1PKM | |
| SCHEMBL4974762 | 0.69 | RORC (0.46) | KMT2AALDH1A1RORCMEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070265270-A1 | Cinnoline derivatives as phosphodiesterase 10 inhibitors | MEMORY PHARMACEUTICALS CORPORATION | 2007-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265270-A1 | Cinnoline derivatives as phosphodiesterase 10 inhibitors | PDE7A, PDE10A, PDE7B | PDE10A 2/4885KMT2A 3459/4885ALDH1A1 416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.