Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | MGAM | O43451 | 6/20 | 0.54 |
| ▸ | GAA | P10253 | 6/20 | 0.54 |
| ▸ | SI | P14410 | 6/20 | 0.54 |
| ▸ | MGAM2 | Q2M2H8 | 6/20 | 0.54 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 2/20 | 0.47 |
| ▸ | FLT3 | P36888 | 2/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5649682 | 0.88 | MAPK8 (0.54) | KDM4EHSD17B10MAPK8PARP1FLT3 | |
| SCHEMBL5652087 | 0.86 | FLT3 (0.49) | HPSEKDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL5649050 | 0.85 | HPSE (0.53) | HPSEKDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL5650962 | 0.85 | MGAM (0.51) | HPSEKDM4EHSD17B10MGAMGAA | |
| SCHEMBL5650424 | 0.84 | HPSE (0.50) | HPSEKDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL5652427 | 0.83 | MAPK8 (0.47) | HPSEMAPK8FLT3 | |
| SCHEMBL5649719 | 0.82 | MGAM (0.48) | HPSEMGAMGAASIMGAM2 | |
| SCHEMBL5648974 | 0.81 | KDM4E (0.53) | KDM4EALDH1A1HPGDSMN1; SMN2PARP1 | |
| SCHEMBL6585826 | 0.81 | HPSE (0.67) | HPSEKDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL5648785 | 0.81 | HPSE (0.53) | HPSEKDM4ESMN1; SMN2HSD17B10MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220769-B2 | Azolylbenzamides and analogues and their use for treating osteoporosis | NIKEM RESEARCH S.R.L. (IT) | 2007-05-22 | — | — | US | disclosed |
| US-20050038095-A1 | Azolylbenzamides and analogues and their use for treating osteoporosis | 3-V BIOSCIENCES, INC. | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038095-A1 | Azolylbenzamides and analogues and their use for treating osteoporosis | NR0B2, NR0B1, NCOR1 | HPSE 3728/4885KDM4E 1605/4885NPC1 1699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.