Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 5/20 | 0.49 |
| ▸ | MGAM | O43451 | 7/20 | 0.48 |
| ▸ | GAA | P10253 | 7/20 | 0.48 |
| ▸ | SI | P14410 | 7/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 7/20 | 0.48 |
| ▸ | APLNR | P35414 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.45 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5650962 | 0.92 | MGAM (0.51) | FLT3MGAMGAASIMGAM2 | |
| SCHEMBL5651896 | 0.92 | FLT3 (0.48) | FLT3MGAMGAASIMGAM2 | |
| SCHEMBL5650424 | 0.91 | HPSE (0.50) | FLT3MGAMGAASIMGAM2 | |
| SCHEMBL5649719 | 0.89 | MGAM (0.48) | FLT3MGAMGAASIMGAM2 | |
| SCHEMBL5648785 | 0.88 | HPSE (0.53) | FLT3MGAMGAASIMGAM2 | |
| SCHEMBL5652419 | 0.86 | HPSE (0.57) | FLT3MGAMGAASIMGAM2 | |
| SCHEMBL5650407 | 0.86 | APLNR (0.47) | MGAMGAASIMGAM2APLNR | |
| SCHEMBL5652092 | 0.84 | FLT3 (0.49) | FLT3APLNRKDM4EHSD17B10GRIN1 | |
| SCHEMBL5652617 | 0.83 | FLT3 (0.45) | FLT3KDM4EHSD17B10HPSEGRIN1 | |
| SCHEMBL5651518 | 0.83 | FLT3 (0.53) | FLT3KDM4EHSD17B10GRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220769-B2 | Azolylbenzamides and analogues and their use for treating osteoporosis | NIKEM RESEARCH S.R.L. (IT) | 2007-05-22 | — | — | US | disclosed |
| US-20050038095-A1 | Azolylbenzamides and analogues and their use for treating osteoporosis | 3-V BIOSCIENCES, INC. | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038095-A1 | Azolylbenzamides and analogues and their use for treating osteoporosis | NR0B2, NR0B1, NCOR1 | FLT3 1968/4885MGAM 3224/4885GAA 4139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.