Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 10/20 | 0.57 |
| ▸ | TAOK1 | Q7L7X3 | 3/20 | 0.56 |
| ▸ | TAOK3 | Q9H2K8 | 2/20 | 0.56 |
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
| ▸ | MMP3 | P08254 | 2/20 | 0.51 |
| ▸ | MMP9 | P14780 | 2/20 | 0.51 |
| ▸ | MMP8 | P22894 | 2/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | NMBR | P28336 | 2/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5652430 | 1.00 | ECE1 (0.57) | ECE1TAOK1TAOK3MMP2MMP3 | |
| SCHEMBL31730289 | 0.82 | TAOK1 (0.60) | ECE1TAOK1TAOK3MMP2MMP3 | |
| SCHEMBL5652426 | 0.82 | TAOK1 (0.60) | ECE1TAOK1TAOK3MMP2MMP3 | |
| SCHEMBL5653439 | 0.82 | TAOK1 (0.60) | ECE1TAOK1TAOK3MMP2MMP3 | |
| SCHEMBL29103332 | 0.78 | ECE1 (0.57) | ECE1TAOK1TAOK3MMP2MMP3 | |
| SCHEMBL5990647 | 0.77 | HDAC1 (0.55) | TAOK1TAOK3 | |
| SCHEMBL5990638 | 0.77 | HDAC1 (0.55) | TAOK1TAOK3 | |
| SCHEMBL5651524 | 0.77 | TAOK3 (0.50) | TAOK1TAOK3 | |
| SCHEMBL5653436 | 0.75 | ALDH1A1 (0.64) | TAOK1TAOK3MMP3MMP9 | |
| SCHEMBL5653425 | 0.75 | ALDH1A1 (0.64) | TAOK1TAOK3MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070208166-A1 | Tao Kinase Modulators And Method Of Use | EXELIXIS, INC. (US) | 2007-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208166-A1 | Tao Kinase Modulators And Method Of Use | TAOK1, TAOK3, MAP3K6 | ECE1 1291/4885TAOK1 1/4885TAOK3 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.