Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAOK1 | Q7L7X3 | 3/20 | 0.60 |
| ▸ | TAOK3 | Q9H2K8 | 2/20 | 0.60 |
| ▸ | SOS1 | Q07889 | 5/20 | 0.58 |
| ▸ | KRAS | P01116 | 1/20 | 0.58 |
| ▸ | ECE1 | P42892 | 6/20 | 0.55 |
| ▸ | MMP2 | P08253 | 2/20 | 0.55 |
| ▸ | MMP3 | P08254 | 2/20 | 0.55 |
| ▸ | MMP9 | P14780 | 2/20 | 0.55 |
| ▸ | MMP8 | P22894 | 2/20 | 0.55 |
| ▸ | NMBR | P28336 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MPO | P05164 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31730289 | 1.00 | TAOK1 (0.60) | TAOK1TAOK3SOS1KRASECE1 | |
| SCHEMBL5652426 | 1.00 | TAOK1 (0.60) | TAOK1TAOK3SOS1KRASECE1 | |
| SCHEMBL5652430 | 0.82 | ECE1 (0.57) | TAOK1TAOK3ECE1MMP2MMP3 | |
| SCHEMBL5652424 | 0.82 | ECE1 (0.57) | TAOK1TAOK3ECE1MMP2MMP3 | |
| SCHEMBL7848819 | 0.82 | MMP2 (0.68) | TAOK1TAOK3ECE1MMP2MMP3 | |
| SCHEMBL7649209 | 0.81 | SOS1 (0.80) | SOS1KRASMMP2MMP9MMP8 | |
| SCHEMBL27798619 | 0.81 | SOS1 (0.80) | SOS1KRASMMP2MMP9MMP8 | |
| SCHEMBL7646131 | 0.80 | SOS1 (0.75) | SOS1KRASMMP2MMP9MMP8 | |
| SCHEMBL7623409 | 0.80 | SOS1 (0.69) | SOS1KRASKDM4EMEN1LMNA | |
| SCHEMBL9825896 | 0.80 | SOS1 (0.75) | SOS1KRASMMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4534091-A1 | INHIBITORY AGENT FOR MYOCARDIAL CELL DEATH, AND PROPHYLACTIC OR THERAPEUTIC AGENT FOR MYOCARDIAL DISORDERS OR HEART FAILURE | KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION (JP) | 2025-04-09 | — | — | EP | disclosed |
| US-20070208166-A1 | Tao Kinase Modulators And Method Of Use | EXELIXIS, INC. (US) | 2007-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208166-A1 | Tao Kinase Modulators And Method Of Use | TAOK1, TAOK3, MAP3K6 | TAOK1 1/4885TAOK3 2/4885SOS1 2285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.