⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57121 | 1.00 | — | — | |
| SCHEMBL310729 | 1.00 | — | — | |
| Ammonia Solution, Strong SCHEMBL3870770 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL14738465 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL4166396 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL6810174 | 0.97 | — | — | |
| Isopropylamine SCHEMBL27579671 | 0.97 | ALDH1A1 (0.39) | — | |
| Bicarbonate SCHEMBL8039500 | 0.86 | GABRP (0.42) | — | |
| SCHEMBL14810548 | 0.80 | TDP1 (0.35) | — | |
| SCHEMBL20181307 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 922 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4452952-A1 | A PREPARATION OF QUINAZOLINEDIONES AND USE THEREOF | Council of Scientific and Industrial Research, an Indian Registered Body Incorporated under Regn. of Soc. Act (Act XXI of 1860) (IN) | 2024-10-30 | — | — | EP | claimed |
| CN-118745165-A | C-N coupling method and method for preparing dimethenamid S configuration by using C-N coupling | 山东京博农化科技股份有限公司 | 2024-10-08 | — | — | CN | claimed |
| CN-118726300-A | Transaminase mutant and application thereof in preparation of oxadiazon intermediate | 浙江工业大学 | 2024-10-01 | — | — | CN | claimed |
| US-12104106-B2 | Compositions of chiral molecules and perovskite nanocrystals and methods of making the same | ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) | 2024-10-01 | — | — | US | claimed |
| CN-118451062-A | Preparation and use of quinazolinediones | 科学与工业研究会(按照印度社会团体注册法案(1860年第21号法案)设立的注册机构) | 2024-08-06 | — | — | CN | claimed |
| CN-117660389-A | Transaminase mutant and application thereof in preparation of chiral amine compounds | 浙江容锐科技有限公司 | 2024-03-08 | — | — | CN | claimed |
| WO-2023119320-A1 | A PREPARATION OF QUINAZOLINEDIONES AND USE THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) | 2023-06-29 | — | — | WO | claimed |
| US-20220326082-A1 | CHIRAL HETEROSTRUCTURES | Alliance for Energy Innovation, LLC | 2022-10-13 | — | — | US | claimed |
| CN-114134126-A | Application of transaminase and mutant thereof in preparation of (S) -1-methoxy-2-propylamine | 浙江大学杭州国际科创中心 | 2022-03-04 | — | — | CN | claimed |
| EP-2763990-B1 | PYRROLOPYRAZINE KINASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2017-02-22 | — | — | EP | claimed |
| EP-1075534-B1 | IMPROVEMENTS IN THE ENZYMATIC SYNTHESIS OF CHIRAL AMINES | CELGRO (US) | 2005-05-11 | — | — | EP | claimed |
| WO-2005026114-A1 | HIV PROTEASE INHIBITORS, COMPOSITIONS CONTAINING THE SAME AND THEIR PHARMACEUTICAL USES | PFIZER INC. (US) | 2005-03-24 | — | — | WO | claimed |
| EP-1075534-A4 | IMPROVEMENTS IN THE ENZYMATIC SYNTHESIS OF CHIRAL AMINES | CELGRO (US) | 2003-07-09 | — | — | EP | claimed |
| EP-1237844-A1 | PROCESS FOR THE PREPARATION OF SECONDARY AND TERTIARY AMINES | Celgro (US) | 2002-09-11 | — | — | EP | claimed |
| WO-2001044162-A1 | PROCESS FOR THE PREPARATION OF SECONDARY AND TERTIARY AMINES | CELGRO (US) | 2001-06-21 | — | — | WO | claimed |
| EP-1075534-A1 | IMPROVEMENTS IN THE ENZYMATIC SYNTHESIS OF CHIRAL AMINES | Celgro (US) | 2001-02-14 | — | — | EP | claimed |
| US-6133018-A | Enzymatic synthesis of chiral amines using -2-amino propane as amine donor | CELGRO (US) | 2000-10-17 | — | — | US | claimed |
| US-6107521-A | Process for the preparation of secondary amines | CELGRO (US) | 2000-08-22 | — | — | US | claimed |
| WO-1999046398-A1 | IMPROVEMENTS IN THE ENZYMATIC SYNTHESIS OF CHIRAL AMINES | CELGRO (US) | 1999-09-16 | — | — | WO | claimed |
| US-5457085-A | Herbicides | SANDOZ LTD. (CH) | 1995-10-10 | — | — | US | claimed |