Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.37 |
| ▸ | CA1 | P00915 | 6/20 | 0.37 |
| ▸ | CA9 | Q16790 | 6/20 | 0.37 |
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13686260 | 0.82 | ALDH1A1 (0.34) | ALDH1A1POLBRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL10814403 | 0.73 | CA2 (0.36) | CA2CA1CA9CA12CA5A | |
| SCHEMBL9663862 | 0.73 | ALDH1A1 (0.49) | ALDH1A1POLBRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL7550351 | 0.73 | CA2 (0.39) | CA2CA1CA9CA12CA5A | |
| SCHEMBL9019517 | 0.69 | PTGS1 (0.38) | ALDH1A1POLBRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL164475 | 0.69 | — | — | |
| SCHEMBL1927671 | 0.69 | CA2 (0.41) | CA2CA1CA9CA12CA5A | |
| SCHEMBL3776935 | 0.69 | CA2 (0.39) | CA2CA1CA9CA12CA5A | |
| SCHEMBL4977235 | 0.69 | CA2 (0.41) | CA2CA1CA9CA12CA5A | |
| SCHEMBL291455 | 0.68 | CA2 (0.58) | CA2CA1CA9CA12CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7084170-B2 | Thiophene-amd thiazolesulfonamides as antineoplastic agents | ELI LILLY AND COMPANY (US) | 2006-08-01 | — | — | US | disclosed |
| EP-0207609-B1 | HERBICIDAL THIOPHENESULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-01-08 | — | — | EP | disclosed |
| US-4877440-A | Thiophenesulfonamide herbicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-10-31 | — | — | US | disclosed |
| US-4743290-A | Thiophenesulfonamide herbicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-05-10 | — | — | US | disclosed |
| EP-0207609-A1 | Herbicidal thiophenesulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-01-07 | — | — | EP | disclosed |