SCHEMBL5652779

SCHEMBL5652779

Nc1ccc(OC2CN3CCC2CC3)cc1

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LSS P48449 1/20 0.57
CHRNA7 P36544 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9469525 0.98 LSS (0.56) LSSCHRNA7
SCHEMBL1542601 0.95 LSS (0.53) LSSCHRNA7
SCHEMBL5416184 0.95 LSS (0.53) LSSCHRNA7
SCHEMBL1542294 0.95 LSS (0.53) LSSCHRNA7
SCHEMBL5710492 0.91 LSS (0.50) LSSCHRNA7
SCHEMBL5390772 0.86 LSS (0.60) LSSCHRNA7
SCHEMBL3215158 0.83 LSS (0.78) LSSCHRNA7
SCHEMBL1849257 0.83 LSS (0.57) LSSCHRNA7
SCHEMBL1018942 0.83 LSS (0.57) LSSCHRNA7
SCHEMBL1542743 0.83 LSS (0.57) LSSCHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023138362-A1 WEE1 INHIBITOR, PREPARATION THEREFOR, AND USE THEREOF 江苏天士力帝益药业有限公司 2023-07-27 WO disclosed
US-7241773-B2 3-quinuclidinyl heteroatom bridged biaryl derivatives ABBOTT LABORATORIES (US) 2007-07-10 US disclosed
US-20050137226-A1 3-Quinuclidinyl heteroatom bridged biaryl derivatives ABBOTT LABORATORIES 2005-06-23 US disclosed
US-20050137398-A1 3-Quinuclidinyl heteroatom bridged biaryl derivatives ABBOTT LABORATORIES 2005-06-23 US disclosed
US-5258392-A 3-quinuclidine derivatives AKZO N.V. (NL) 1993-11-02 US disclosed
EP-0497415-A1 3-Quinuclidine derivatives Akzo Nobel N.V. (NL) 1992-08-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050137398-A1 3-Quinuclidinyl heteroatom bridged biaryl derivatives CHRNA1, CHRNA2, CHRM2 LSS 2314/4885CHRNA7 8/4885
US-20050137226-A1 3-Quinuclidinyl heteroatom bridged biaryl derivatives CHRNA3, CHRNA1, CHRM3 LSS 1730/4885CHRNA7 11/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.