Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.54 |
| ▸ | CCR8 | P51685 | 2/20 | 0.43 |
| ▸ | GPR39 | O43194 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5650218 | 0.91 | KCNH2 (0.47) | KCNH2CCR8GPR39MTNR1AMTNR1B | |
| SCHEMBL3692223 | 0.75 | KCNH2 (0.40) | KCNH2CCR8MTNR1AMTNR1BSLC2A1 | |
| SCHEMBL13146379 | 0.72 | SLC2A1 (0.58) | KCNH2SLC2A1 | |
| SCHEMBL5646708 | 0.72 | MTNR1A (0.46) | KCNH2MTNR1AMTNR1BSLC2A1 | |
| SCHEMBL7462927 | 0.71 | CCR8 (0.54) | KCNH2CCR8 | |
| SCHEMBL13145572 | 0.71 | KCNH2 (0.65) | KCNH2CCR8 | |
| SCHEMBL7724073 | 0.71 | KCNH2 (0.53) | KCNH2CCR8 | |
| SCHEMBL3248917 | 0.70 | KCNH2 (0.59) | KCNH2CCR8MTNR1AMTNR1B | |
| SCHEMBL6975577 | 0.70 | KCNH2 (0.58) | KCNH2 | |
| SCHEMBL3697078 | 0.70 | LMNA (0.40) | KCNH2MTNR1AMTNR1BSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223776-B2 | Compounds with anti-bacterial activity | MORPHOCHEM AG (DE) | 2007-05-29 | — | — | US | disclosed |
| US-20060040949-A1 | Novel compounds with antibacterial activity | MORPHOCHEM AG | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060040949-A1 | Novel compounds with antibacterial activity | MRPL21, Q6ZSR9, MRPL19 | KCNH2 2411/4885CCR8 3798/4885GPR39 3098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.