Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | CDC7 | O00311 | 3/20 | 0.45 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5651454 | 0.90 | ALDH1A1 (0.54) | MEN1KMT2AMAPTPOLBCDC7 | |
| SCHEMBL27617043 | 0.87 | FEN1 (0.41) | GABRA1GABRA5KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL5651499 | 0.85 | MDM2 (0.51) | MEN1KMT2AKDM4EMAPTCDC7 | |
| SCHEMBL5648462 | 0.83 | MAPK8 (0.51) | MEN1KMT2AKDM4EMAPTNPC1 | |
| SCHEMBL5650191 | 0.83 | ALDH1A1 (0.47) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL5651710 | 0.83 | MEN1 (0.46) | MEN1KMT2AKDM4EMAPTNPC1 | |
| SCHEMBL5652931 | 0.82 | ACACB (0.53) | MEN1KMT2AKDM4EMAPTNPC1 | |
| SCHEMBL5651778 | 0.81 | MEN1 (0.48) | MEN1KMT2AKDM4EMAPTNPC1 | |
| SCHEMBL5651409 | 0.80 | ALDH1A1 (0.45) | MEN1KMT2AKDM4EMAPTPOLB | |
| SCHEMBL5653004 | 0.80 | ALDH1A1 (0.41) | MEN1KMT2AKDM4EMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176215-B2 | Bicyclic oxopyridine and oxopyrimidine derivatives | CELLTECH R&D LIMITED (GB) | 2007-02-13 | — | — | US | disclosed |
| US-20040254200-A1 | Bicyclic oxopyridine and oxopyrimidine derivatives | UCB PHARMA S.A. (BE) | 2004-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254200-A1 | Bicyclic oxopyridine and oxopyrimidine derivatives | MAPK1, ALK, NAT1 | GABRA1 2437/4885GABRA5 3576/4885MEN1 4697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.