SCHEMBL565341

SCHEMBL565341

O=C(O)CCCC(F)(F)F

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.53
SLC22A6 Q4U2R8 2/20 0.53
TSHR P16473 4/20 0.50
NFKB1 P19838 2/20 0.50
PMP22 Q01453 1/20 0.50
CAMK2A Q9UQM7 1/20 0.46
OXER1 Q8TDS5 1/20 0.45
HDAC11 Q96DB2 3/20 0.43
KMT2A Q03164 2/20 0.43
GABRR3 A8MPY1 1/20 0.43
GABRP O00591 1/20 0.43
GABRD O14764 1/20 0.43
HDAC3 O15379 1/20 0.43
GABBR2 O75899 1/20 0.43
CYP1A2 P05177 1/20 0.43
THRB P10828 1/20 0.43
GABRA1 P14867 1/20 0.43
GABRB1 P18505 1/20 0.43
GABRG2 P18507 1/20 0.43
GABRR1 P24046 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28492068 0.97 LMNA (0.50) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL866445 0.92 LMNA (0.58) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL8759579 0.90 TSHR (0.60) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL10442027 0.90 TSHR (0.60) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL5247469 0.90 TSHR (0.60) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL19706336 0.90 TSHR (0.60) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL7813622 0.90 TSHR (0.60) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL5249605 0.90 TSHR (0.60) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL21850118 0.90 TSHR (0.60) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL10442148 0.90 TSHR (0.60) LMNASLC22A6TSHRNFKB1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 503 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025025370-A1 COATING COMPOSITION HAVING MOLD-PROOF AND ANTIBACTERIAL PROPERTIES AND PREPARATION METHOD THEREFOR 江西永通科技股份有限公司 2025-02-06 WO claimed
CN-108538572-B Capacitor packaging structure 钰邦电子(无锡)有限公司 2020-09-04 CN claimed
CN-107502412-B High-temperature-resistant magnesium salt lubricating oil detergent and preparation method thereof 黄山学院 2020-02-14 CN claimed
US-10361036-B2 Capacitor package structure APAQ TECHNOLOGY CO., LTD. (TW) 2019-07-23 US claimed
CN-108538572-A Capacitor packaging structure 钰邦电子(无锡)有限公司 2018-09-14 CN claimed
US-20180254148-A1 CAPACITOR PACKAGE STRUCTURE APAQ TECHNOLOGY CO., LTD. (TW) 2018-09-06 US claimed
CN-107502412-A A kind of high temperature resistant type magnesium salts detergent for lubricating oil and preparation method thereof 黄山学院 2017-12-22 CN claimed
US-7772221-B2 Diaminopropane derived macrocycles as inhibitors of β amyloid production BRISTOL-MEYERS SQUIBB COMPANY (US) 2010-08-10 US claimed
US-20080194535-A1 DIAMINOPROPANE DERIVED MACROCYCLES AS INHIBITORS OF BETA AMYLOID PRODUCTION BRISTOL-MYERS SQUIBB COMPANY 2008-08-14 US claimed
EP-4029868-B1 MCL-1 INHIBITORS GILEAD SCIENCES INC (US) 2026-05-20 EP disclosed
EP-4737477-A2 HEPCIDIN MIMETICS FOR TREATMENT OF HEREDITARY HEMOCHROMATOSIS Protagonist Therapeutics, Inc. (US) 2026-05-06 EP disclosed
EP-4706671-A2 CONJUGATED HEPCIDIN MIMETICS Protagonist Therapeutics, Inc. (US) 2026-03-11 EP disclosed
EP-4700017-A2 FLUORINATED CATIONIC LIPIDS FOR USE IN LIPID NANOPARTICLES Acuitas Therapeutics Inc. (CA) 2026-02-25 EP disclosed
US-20260035359-A1 HERBICIDAL IMIDAZOLE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2026-02-05 US disclosed
US-4895587-A Haloacetamide compounds, process for production thereof, and use thereof as herbicide TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1990-01-23 US disclosed
EP-0206251-B1 HALOACETAMIDE COMPOUNDS, PROCESS FOR PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDE TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1988-09-07 EP disclosed
CN-87102455-A Diphenyl ether derivatives pesticide compound 1988-01-27 CN disclosed
US-4552883-A CNS DEPRESSANTS, ANXIOLYTICS ICI AMERICAS INC. (US) 1985-11-12 US disclosed
EP-0096995-A2 Pyrazolopyridine compounds ICI AMERICAS INC. (US) 1983-12-28 EP disclosed
US-3957672-A FLUORINATED POLYETHERS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080194535-A1 DIAMINOPROPANE DERIVED MACROCYCLES AS INHIBITORS OF BETA AMYLOID PRODUCTION APP, BACE1, BACE2 LMNA 489/4885SLC22A6 3048/4885TSHR 3180/4885
US-20260035359-A1 HERBICIDAL IMIDAZOLE COMPOUNDS CBR3, CBR1, CLIC1 LMNA 3581/4885SLC22A6 2493/4885TSHR 864/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.