Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 5/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 8/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1332529 | 0.91 | ADORA1 (0.42) | ADORA1ADORA2BADORA2AADORA3KMT2A | |
| SCHEMBL1332404 | 0.91 | ADORA2B (0.44) | ADORA1ADORA2BADORA2AADORA3TSHR | |
| Hydrochloric Acid SCHEMBL1332577 | 0.91 | ADORA2B (0.43) | ADORA1ADORA2BADORA2AADORA3TSHR | |
| SCHEMBL1332763 | 0.89 | ADORA1 (0.41) | ADORA1ADORA2BADORA2AADORA3KMT2A | |
| SCHEMBL1333085 | 0.88 | ADORA1 (0.41) | ADORA1ADORA2BADORA2AADORA3KMT2A | |
| SCHEMBL4176171 | 0.88 | ADORA1 (0.41) | ADORA1ADORA2BADORA2AADORA3KMT2A | |
| SCHEMBL1332443 | 0.87 | ADORA1 (0.40) | ADORA1ADORA2BADORA2AADORA3KMT2A | |
| SCHEMBL1334668 | 0.87 | ADORA1 (0.42) | ADORA1ADORA2BADORA2AADORA3TSHR | |
| SCHEMBL1333189 | 0.86 | ADORA3 (0.40) | ADORA1ADORA2BADORA2AADORA3KMT2A | |
| SCHEMBL1334307 | 0.86 | ADORA2B (0.47) | ADORA1ADORA2BADORA2AADORA3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247639-B2 | A1 adenosine receptor antagonists | ENDACEA, INC. (US) | 2007-07-24 | — | — | US | claimed |