Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.64 |
| ▸ | RAB9A | P51151 | 9/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.64 |
| ▸ | CASP2 | P42575 | 1/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA7 | P43166 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | SCD | O00767 | 4/20 | 0.60 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24846611 | 0.81 | MAPT (0.63) | NPC1RAB9ASMN1; SMN2HTTCYP1A2 | |
| SCHEMBL2759560 | 0.81 | RAB9A (0.65) | NPC1RAB9ASMN1; SMN2HTTCYP1A2 | |
| SCHEMBL31390761 | 0.81 | CA12 (0.60) | NPC1RAB9ASMN1; SMN2HTTCYP1A2 | |
| SCHEMBL5653636 | 0.80 | CASP2 (0.77) | NPC1RAB9ASMN1; SMN2HTTCYP1A2 | |
| SCHEMBL30526514 | 0.79 | CA12 (0.61) | NPC1RAB9ASMN1; SMN2HTTCYP1A2 | |
| SCHEMBL31390763 | 0.79 | CA12 (0.54) | NPC1RAB9ASMN1; SMN2HTTCYP1A2 | |
| SCHEMBL21814758 | 0.79 | QPCT (0.63) | NPC1RAB9ASMN1; SMN2HTTCYP1A2 | |
| SCHEMBL30526515 | 0.79 | CA12 (0.60) | NPC1RAB9ASMN1; SMN2HTTCYP1A2 | |
| SCHEMBL30526513 | 0.79 | CA12 (0.60) | NPC1RAB9ASMN1; SMN2HTTCYP1A2 | |
| SCHEMBL30526526 | 0.79 | CA12 (0.60) | NPC1RAB9ASMN1; SMN2HTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070208166-A1 | Tao Kinase Modulators And Method Of Use | EXELIXIS, INC. (US) | 2007-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208166-A1 | Tao Kinase Modulators And Method Of Use | TAOK1, TAOK3, MAP3K6 | NPC1 3827/4885RAB9A 1857/4885SMN1; SMN2 4552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.