Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2214956 | 1.00 | TSHR (0.37) | TSHRKIF11CYP3A4CYP2D6NFKB1 | |
| SCHEMBL2214960 | 1.00 | TSHR (0.37) | TSHRKIF11CYP3A4CYP2D6NFKB1 | |
| SCHEMBL14150765 | 0.92 | SLC7A5 (0.41) | KIF11SLC7A5NOS1NOS2NOS3 | |
| SCHEMBL14150764 | 0.92 | SLC7A5 (0.41) | KIF11SLC7A5NOS1NOS2NOS3 | |
| SCHEMBL20215620 | 0.92 | KIF11 (0.38) | TSHRKIF11SMN1; SMN2CA12CA1 | |
| SCHEMBL24374504 | 0.92 | SLC7A5 (0.41) | KIF11SLC7A5NOS1NOS2NOS3 | |
| SCHEMBL14227090 | 0.91 | TSHR (0.31) | TSHRKIF11 | |
| SCHEMBL23743117 | 0.87 | TSHR (0.37) | TSHRKIF11LMNASLC7A5CYP4F2 | |
| SCHEMBL27725195 | 0.83 | TSHR (0.31) | TSHR | |
| SCHEMBL23743097 | 0.83 | METAP2 (0.40) | TSHRKIF11LMNASLC7A5CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450089-B2 | Compounds as L-cystine crystallization inhibitors and uses thereof | NEW YORK UNIVERSITY (US) | 2013-05-28 | — | — | US | claimed |
| US-9988409-B2 | Multi-dimensional networks | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-06-05 | — | — | US | disclosed |
| US-20140205846-A1 | MULTI-DIMENSIONAL NETWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-07-24 | — | — | US | disclosed |
| US-7105570-B2 | Cysteine derivatives | AJINOMOTO CO., INC. (JP) | 2006-09-12 | — | — | US | disclosed |
| US-6852378-B2 | Sheet for ink jet-recording | OJI PAPER CO., LTD. (JP) | 2005-02-08 | — | — | US | disclosed |
| US-20040058099-A1 | Sheet for ink jet-recording | OJI PAPER CO., LTD. | 2004-03-25 | — | — | US | disclosed |
| US-6703031-B1 | OXIDATIVE STRESS INHIBITOR; RETARDING AGING OF SKIN | AJINOMOTO CO., INC. (JP) | 2004-03-09 | — | — | US | disclosed |
| US-6602492-B2 | Cysteine derivatives | AJINOMOTO CO., INC. (JP) | 2003-08-05 | — | — | US | disclosed |
| EP-1120407-A1 | CYSTEINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2001-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140205846-A1 | MULTI-DIMENSIONAL NETWORKS | DCX, CCNB2, CCNA2 | TSHR 4327/4885KIF11 376/4885CYP3A4 1702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.