Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 6/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70013 | 0.93 | TYR (0.66) | TYRCYP3A4MAPTMEN1TP53 | |
| SCHEMBL29457621 | 0.86 | TYR (0.49) | TYRCYP3A4MAPTMEN1TP53 | |
| SCHEMBL10783247 | 0.86 | TYR (0.49) | TYRCYP3A4MAPTMEN1TP53 | |
| SCHEMBL3461803 | 0.86 | TYR (0.49) | TYRCYP3A4MAPTMEN1TP53 | |
| SCHEMBL31545069 | 0.85 | TYR (0.76) | TYRCYP3A4MAPTMEN1TP53 | |
| SCHEMBL940625 | 0.85 | TYR (0.76) | TYRCYP3A4MAPTMEN1TP53 | |
| SCHEMBL8401997 | 0.85 | TYR (0.81) | TYRCYP3A4MAPTMEN1TP53 | |
| SCHEMBL8398763 | 0.85 | TYR (0.81) | TYRCYP3A4MAPTMEN1TP53 | |
| SCHEMBL8401879 | 0.85 | TYR (0.81) | TYRCYP3A4MAPTMEN1TP53 | |
| SCHEMBL8398793 | 0.85 | TYR (0.81) | TYRCYP3A4MAPTMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1282730-A | Compounds with particular structure and anticancer activity and its preparing process | YANG ZHENHUA (CN) | 2001-02-07 | — | — | CN | claimed |
| US-7109364-B2 | Group of anti-cancer compounds with specific structure and their production method | YANG ZHENHUA | 2006-09-19 | — | — | US | disclosed |
| EP-1259470-A4 | A GROUP OF ANTI-CANCER COMPOUNDS WITH SPECIFIC STRUCTURE AND THEIR PRODUCTION METHOD | YANG ZHENHUA (US) | 2005-06-15 | — | — | EP | disclosed |
| CN-1193002-C | Compounds with particular structure and anticancer activity and its preparing process | YANG ZHENHUA (CN) | 2005-03-16 | — | — | CN | disclosed |
| US-20040034242-A1 | Group of anti-cancer compounds with specific structure and their production method | YANG ZHENHUA (US) | 2004-02-19 | — | — | US | disclosed |
| EP-1259470-A2 | A GROUP OF ANTI-CANCER COMPOUNDS WITH SPECIFIC STRUCTURE AND THEIR PRODUCTION METHOD | Yang, Zhenhua (US) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001059067-A2 | A GROUP OF ANTI-CANCER COMPOUNDS WITH SPECIFIC STRUCTURE AND THEIR PRODUCTION METHOD | YANG ZHENHUA (US) | 2001-08-16 | — | — | WO | disclosed |
| CN-1282730-A | Compounds with particular structure and anticancer activity and its preparing process | YANG ZHENHUA (CN) | 2001-02-07 | — | — | CN | disclosed |