Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 6/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.81 |
| ▸ | MAPT | P10636 | 2/20 | 0.81 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.81 |
| ▸ | MEN1 | O00255 | 1/20 | 0.81 |
| ▸ | TP53 | P04637 | 1/20 | 0.81 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.81 |
| ▸ | TSHR | P16473 | 1/20 | 0.81 |
| ▸ | HTT | P42858 | 1/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8401997 | 1.00 | TYR (0.81) | TYRCYP3A4MAPTALOX5MEN1 | |
| SCHEMBL8401879 | 1.00 | TYR (0.81) | TYRCYP3A4MAPTALOX5MEN1 | |
| SCHEMBL8398793 | 1.00 | TYR (0.81) | TYRCYP3A4MAPTALOX5MEN1 | |
| SCHEMBL4370686 | 0.93 | TYR (0.81) | TYRCYP3A4MAPTALOX5MEN1 | |
| SCHEMBL1846489 | 0.92 | TYR (0.70) | TYRCYP3A4MAPTALOX5MEN1 | |
| SCHEMBL70910 | 0.90 | TYR (1.00) | TYRCYP3A4MAPTALOX5MEN1 | |
| Hexylresorcinol SCHEMBL29107 | 0.90 | TYR (1.00) | TYRCYP3A4MAPTALOX5MEN1 | |
| SCHEMBL6334759 | 0.90 | TYR (1.00) | TYRCYP3A4MAPTALOX5MEN1 | |
| SCHEMBL69504 | 0.90 | TYR (1.00) | TYRCYP3A4MAPTALOX5MEN1 | |
| SCHEMBL13609128 | 0.90 | TYR (1.00) | TYRCYP3A4MAPTALOX5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859067-A | PREPARING BIS(2-HYDROXY-1-NAPHTHYL)DECANE FROM THE CORRESPONDING DIACID; FORMING ACID DICHLORIDE; TREATING WITH 2-NAPHTHOL; REARRANGEMENT; REDUCTION; INHIBITS ACTION OF ADENOSINE TRIPHOSPHATASE | ROUFOGALIS BASIL DON (AU) | 1999-01-12 | — | — | US | disclosed |
| US-5741821-A | PHENOLIC ENZYME INHIBITORS | THE UNIVERSITY OF SYDNEY (AU) | 1998-04-21 | — | — | US | disclosed |
| WO-1994028886-A1 | USE OF NATURAL PRODUCTS AND RELATED SYNTHETIC COMPOUNDS FOR THE TREATMENT OF CARDIOVASCULAR DISEASE | THE UNIVERSITY OF SYDNEY (AU) | 1994-12-22 | — | — | WO | disclosed |