Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 6/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5654220 | 0.93 | TYR (0.67) | TYRMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL31545069 | 0.89 | TYR (0.76) | TYRMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL940625 | 0.89 | TYR (0.76) | TYRMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL9356596 | 0.86 | TYR (0.63) | TYRMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL69672 | 0.85 | TYR (0.47) | TYRMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL12464338 | 0.82 | TYR (0.45) | TYRMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL4370686 | 0.82 | TYR (0.81) | TYRMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL4420957 | 0.82 | TYR (0.57) | TYRMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL8401879 | 0.80 | TYR (0.81) | TYRMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL8401997 | 0.80 | TYR (0.81) | TYRMEN1TP53CYP3A4ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11129781-B2 | Agent for hair deforming treatment | KAO CORPORATION (JP) | 2021-09-28 | — | — | US | disclosed |
| US-11045402-B2 | Hair cosmetic composition | KAO CORPORATION (JP) | 2021-06-29 | — | — | US | disclosed |
| US-10959925-B2 | Hair cosmetic composition | KAO CORPORATION (JP) | 2021-03-30 | — | — | US | disclosed |
| EP-3228302-B1 | HAIR DEFORMATION TREATMENT AGENT | KAO CORP (JP) | 2020-09-02 | — | — | EP | disclosed |
| CN-106999382-B | Hair deforming agent | 花王株式会社 | 2020-07-10 | — | — | CN | disclosed |
| CN-106999380-B | Hair deforming agent | 花王株式会社 | 2020-05-05 | — | — | CN | disclosed |
| US-20190290564-A1 | HAIR COSMETIC COMPOSITION | KAO CORPORATION (JP) | 2019-09-26 | — | — | US | disclosed |
| US-20190254943-A1 | HAIR COSMETIC COMPOSITION | KAO CORPORATION (JP) | 2019-08-22 | — | — | US | disclosed |
| US-20190224093-A1 | HAIR COSMETIC COMPOSITION | KAO CORPORATION (JP) | 2019-07-25 | — | — | US | disclosed |
| US-20190125052-A1 | METHOD FOR TREATING HAIR | KAO CORPORATION (JP) | 2019-05-02 | — | — | US | disclosed |
| US-4996178-A | Catalyst system containing organophosphorus compound and acid acceptor | THE GOODYEAR TIRE & RUBBER CO. (US) | 1991-02-26 | — | — | US | disclosed |
| US-4923839-A | CATALYST OF ACID ACCEPTOR POLYMER, HALOGENATED ORGANIC COMPOUND, PHENYLPHOSPHINE COMPOUND | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1990-05-08 | — | — | US | disclosed |
| US-4895922-A | In presence of acid acceptor, halogenated compound, and triphenylphosphine oxide | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1990-01-23 | — | — | US | disclosed |
| US-4895817-A | LOW TEMPERATURE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1990-01-23 | — | — | US | disclosed |
| US-4843053-A | CATALYST SYSTEM CONTAINING A PHOSPHORUS COMPOUND, LEWIS BASE, AND HALOGENATED ORGANIC COMPOUND | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1989-06-27 | — | — | US | disclosed |
| US-4804730-A | HEATING AT LOW TEMPERATURES | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1989-02-14 | — | — | US | disclosed |
| EP-0292629-A2 | Polycondensation catalyst | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-11-30 | — | — | EP | disclosed |
| US-4778873-A | MIXTURE OF PHOSPHORUS-SILICON COMPOUND AND ACID ACCEPTOR | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1988-10-18 | — | — | US | disclosed |
| EP-0277907-A2 | Low temperature synthesis of condensation polymers | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-08-10 | — | — | EP | disclosed |
| US-4668762-A | OXYGEN-SILICON-PHOSPHORUS-CONTAINING COMPOUNDS, ACID ACCEPTORS AND HALO COMPOUND TO MAKE POLYESTERS,-UREAS AND AMIDES AT LOW TEMPERATURE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1987-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11045402-B2 | Hair cosmetic composition | CUTA, GRHPR, POLR1C | TYR 6/4885MEN1 1443/4885TP53 260/4885 |
| US-10959925-B2 | Hair cosmetic composition | CUTA, POLR1C, GRHPR | TYR 4/4885MEN1 1687/4885TP53 70/4885 |
| US-20190254943-A1 | HAIR COSMETIC COMPOSITION | CUTA, POLR1C, GRHPR | TYR 4/4885MEN1 1687/4885TP53 70/4885 |
| US-20190125052-A1 | METHOD FOR TREATING HAIR | GRHPR, TYR, POLR1C | TYR 2/4885MEN1 2426/4885TP53 850/4885 |
| US-20190224093-A1 | HAIR COSMETIC COMPOSITION | CUTA, GRHPR, POLR1C | TYR 6/4885MEN1 1443/4885TP53 260/4885 |
| US-11129781-B2 | Agent for hair deforming treatment | GRHPR, SLC26A4, COL1A1 | TYR 98/4885MEN1 1850/4885TP53 738/4885 |
| US-20190290564-A1 | HAIR COSMETIC COMPOSITION | GRHPR, POLR1C, TYR | TYR 3/4885MEN1 1122/4885TP53 106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.