Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.58 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5655438 | 0.80 | TAOK1 (0.64) | TAOK1TAOK3TSHRADAMTS5LMNA | |
| SCHEMBL14422166 | 0.74 | TAOK1 (1.00) | TAOK1TAOK3TSHRMEN1KMT2A | |
| SCHEMBL8803934 | 0.69 | TSHR (0.54) | TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1508212 | 0.68 | APP (0.56) | TAOK1TAOK3 | |
| SCHEMBL9189704 | 0.66 | MCL1 (0.51) | MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8343410 | 0.66 | MCL1 (0.51) | MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL13201629 | 0.65 | MEN1 (0.52) | MEN1KMT2ALMNA | |
| SCHEMBL20473309 | 0.65 | FFAR1 (0.59) | TAOK1TAOK3TSHRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL30466486 | 0.65 | MCL1 (0.50) | MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL1432953 | 0.64 | POLB (0.54) | MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070208166-A1 | Tao Kinase Modulators And Method Of Use | EXELIXIS, INC. (US) | 2007-09-06 | — | — | US | claimed |
| US-20070208166-A1 | Tao Kinase Modulators And Method Of Use | EXELIXIS, INC. (US) | 2007-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208166-A1 | Tao Kinase Modulators And Method Of Use | TAOK1, TAOK3, MAP3K6 | TAOK1 1/4885TAOK3 2/4885TSHR 2539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.