Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 1.00 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | STAT5A | P42229 | 1/20 | 0.50 |
| ▸ | STAT5B | P51692 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.48 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.48 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15145896 | 0.87 | TAOK1 (0.77) | TAOK1TAOK3POLBSTAT5ASTAT5B | |
| SCHEMBL15145811 | 0.81 | POLB (0.74) | TAOK1TAOK3POLBSGMS1ALDH1A1 | |
| SCHEMBL5655438 | 0.78 | TAOK1 (0.64) | TAOK1TAOK3POLBSTAT5ASTAT5B | |
| SCHEMBL22669039 | 0.77 | TAOK1 (0.62) | TAOK1TAOK3POLBGRIN1GRIN2B | |
| SCHEMBL28676262 | 0.77 | ERCC1 (0.68) | TAOK1TAOK3TSHRADORA2BADORA1 | |
| SCHEMBL9265107 | 0.75 | LMNA (0.66) | TAOK1TAOK3POLBSGMS1ALDH1A1 | |
| SCHEMBL18130478 | 0.75 | TRPV1 (0.59) | TAOK1TAOK3POLBTSHRALDH1A1 | |
| SCHEMBL16270961 | 0.75 | KMT2A (0.62) | TAOK1TAOK3POLBKMT2AMEN1 | |
| SCHEMBL28668952 | 0.75 | KMT2A (0.68) | TAOK1TAOK3ERCC1ERCC4ALDH1A1 | |
| SCHEMBL5655441 | 0.74 | TAOK1 (0.58) | TAOK1TAOK3TSHRADAMTS5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250354151-A1 | INHIBITORY AGENT FOR MYOCARDIAL CELL DEATH, AND PROPHYLACTIC OR THERAPEUTIC AGENT FOR MYOCARDIAL DISORDERS OR HEART FAILURE | KYOTO PREFECTURAL PUBLIC UNIV CORP (JP) | 2025-11-20 | — | — | US | disclosed |
| EP-4534091-A1 | INHIBITORY AGENT FOR MYOCARDIAL CELL DEATH, AND PROPHYLACTIC OR THERAPEUTIC AGENT FOR MYOCARDIAL DISORDERS OR HEART FAILURE | KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION (JP) | 2025-04-09 | — | — | EP | disclosed |
| US-20070208166-A1 | Tao Kinase Modulators And Method Of Use | EXELIXIS, INC. (US) | 2007-09-06 | — | — | US | disclosed |
| US-20070208166-A1 | Tao Kinase Modulators And Method Of Use | EXELIXIS, INC. (US) | 2007-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250354151-A1 | INHIBITORY AGENT FOR MYOCARDIAL CELL DEATH, AND PROPHYLACTIC OR THERAPEUTIC AGENT FOR MYOCARDIAL DISORDERS OR HEART FAILURE | TNNI3, TNNC1, TNNT2 | TAOK1 7/4885TAOK3 16/4885POLB 4646/4885 |
| US-20070208166-A1 | Tao Kinase Modulators And Method Of Use | TAOK1, TAOK3, MAP3K6 | TAOK1 1/4885TAOK3 2/4885POLB 1548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.