Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5656444 | 0.96 | KCNH2 (0.36) | KCNH2ICAM1SLC2A1 | |
| SCHEMBL14573142 | 0.80 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL5764669 | 0.79 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL14434676 | 0.77 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL6218218 | 0.77 | SLC2A1 (0.39) | KCNH2SLC2A1 | |
| SCHEMBL5746077 | 0.77 | KCNH2 (0.40) | KCNH2 | |
| SCHEMBL5264336 | 0.76 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL5777425 | 0.76 | KCNH2 (0.40) | KCNH2 | |
| SCHEMBL14573152 | 0.76 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL5750648 | 0.76 | KCNH2 (0.39) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186730-B2 | Bicyclic nitrogen-containing heterocyclic derivatives for use as antibacterials | SMITHKLINE BEECHAM P.L.C. (GB) | 2007-03-06 | — | — | US | claimed |