Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5654673 | 0.88 | MAPT (0.56) | DRD2ADRA1ADRD3MEN1KMT2A | |
| SCHEMBL5657975 | 0.86 | MAPT (0.59) | MEN1KMT2AHTR7NPC1HSD17B10 | |
| SCHEMBL5655919 | 0.86 | KMT2A (0.53) | DRD2ADRA1ADRD3MEN1KMT2A | |
| SCHEMBL14457597 | 0.85 | DRD2 (0.52) | DRD2MEN1KMT2AHTR7NPC1 | |
| SCHEMBL5657782 | 0.85 | KMT2A (0.63) | MEN1KMT2AHTR7NPC1HTR1A | |
| SCHEMBL5656137 | 0.85 | NPC1 (0.51) | MEN1KMT2AHTR7NPC1HTR1A | |
| SCHEMBL6190931 | 0.85 | MAPT (0.52) | DRD2ADRA1ADRD3MEN1KMT2A | |
| SCHEMBL5657841 | 0.85 | HTR1A (0.55) | MEN1KMT2AHTR7NPC1HTR1A | |
| SCHEMBL5656207 | 0.84 | NPC1 (0.65) | DRD2MEN1KMT2ANPC1HTR1A | |
| SCHEMBL6753306 | 0.84 | KMT2A (0.45) | MEN1KMT2AHTR7NPC1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238693-B2 | Aryl carbamate derivatives, preparation and use thereof | CEREP (FR) | 2007-07-03 | — | — | US | disclosed |
| US-7238693-B2 | Aryl carbamate derivatives, preparation and use thereof | CEREP (FR) | 2007-07-03 | — | — | US | disclosed |
| EP-1362041-A1 | ARYL CARBAMATE DERIVATIVES, PREPARATION AND USE THEREOF | Cerep (FR) | 2003-11-19 | — | — | EP | disclosed |
| WO-2002068399-A1 | ARYL CARBAMATE DERIVATIVES, PREPARATION AND USE THEREOF | CEREP (FR) | 2002-09-06 | — | — | WO | disclosed |