Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | G6PD | P11413 | 1/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9121900 | 0.92 | MAPT (0.65) | MAPTMEN1KMT2AL3MBTL1HPGD | |
| SCHEMBL9117636 | 0.89 | MAPT (0.62) | MAPTMEN1KMT2AL3MBTL1HPGD | |
| SCHEMBL9119799 | 0.88 | EPAS1 (0.57) | MAPTMEN1KMT2AHPGDLMNA | |
| SCHEMBL9119530 | 0.84 | MAPK1 (0.51) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL29485957 | 0.81 | LMNA (0.59) | MAPTMEN1KMT2AHPGDLMNA | |
| SCHEMBL1119379 | 0.81 | LMNA (0.59) | MAPTMEN1KMT2AHPGDLMNA | |
| SCHEMBL23565733 | 0.81 | KMT2A (0.61) | MEN1KMT2AHPGDLMNAALDH1A1 | |
| SCHEMBL4932340 | 0.79 | MAPT (0.73) | MAPTMEN1KMT2AL3MBTL1HPGD | |
| SCHEMBL16485908 | 0.78 | MAPT (0.48) | MAPTMEN1KMT2AL3MBTL1HPGD | |
| SCHEMBL9888489 | 0.78 | AKR1C3 (0.60) | MAPTMEN1KMT2AL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244756-B2 | Benzimidazol-2-one derivatives and their use | POSEIDON PHARMACEUTICALS A/S (DK) | 2007-07-17 | — | — | US | disclosed |
| US-20050250832-A1 | For increasing blood-brain barrier permeability | ANIONA APS (DK) | 2005-11-10 | — | — | US | disclosed |
| EP-1519923-A1 | NOVEL BENZIMIDAZOL-2-ONE DERIVATIVES AND THEIR USE | Poseidon Pharmaceuticals A/S (DK) | 2005-04-06 | — | — | EP | disclosed |
| WO-2004002962-A1 | NOVEL BENZIMIDAZOL-2-ONE DERIVATIVES AND THEIR USE | POSEIDON PHARMACEUTICALS A/S (DK) | 2004-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250832-A1 | For increasing blood-brain barrier permeability | FABP7, AQP4, SLC2A2 | MAPT 1119/4885MEN1 3793/4885KMT2A 3967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.