Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.73 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.65 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.63 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | IDO1 | P14902 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | CTSV | O60911 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4575162 | 0.92 | AKR1C3 (0.70) | MAPTL3MBTL1MAPK1TDP1ALDH1A1 | |
| SCHEMBL4744863 | 0.89 | MAPT (0.64) | MAPTL3MBTL1MAPK1TDP1ALDH1A1 | |
| SCHEMBL11383159 | 0.87 | L3MBTL1 (0.82) | MAPTL3MBTL1MAPK1TDP1ALDH1A1 | |
| SCHEMBL2309318 | 0.84 | MAPT (1.00) | MAPTL3MBTL1MAPK1TDP1ALDH1A1 | |
| SCHEMBL4933766 | 0.84 | MAPT (0.67) | MAPTL3MBTL1MAPK1TDP1ALDH1A1 | |
| SCHEMBL2902330 | 0.83 | MAPT (0.65) | MAPTL3MBTL1MAPK1TDP1ALDH1A1 | |
| SCHEMBL15201798 | 0.83 | MAPT (0.73) | MAPTL3MBTL1MAPK1TDP1ALDH1A1 | |
| SCHEMBL2328384 | 0.83 | MAPT (0.58) | MAPTL3MBTL1MAPK1TDP1ALDH1A1 | |
| SCHEMBL4922797 | 0.83 | L3MBTL1 (0.63) | MAPTL3MBTL1MAPK1TDP1ALDH1A1 | |
| SCHEMBL14656691 | 0.82 | MAPT (0.84) | MAPTL3MBTL1MAPK1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080021069-A1 | Receptor Function Regulating Agent | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-24 | — | — | US | disclosed |
| EP-1810677-A1 | RECEPTOR FUNCTION REGULATING AGENT | Takeda Pharmaceutical Company Limited (JP) | 2007-07-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021069-A1 | Receptor Function Regulating Agent | GPR119, INSR, GPR65 | MAPT 4574/4885L3MBTL1 4264/4885MAPK1 884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.