Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 16/20 | 0.46 |
| ▸ | CNR1 | P21554 | 5/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL476654 | 0.86 | P2RX7 (0.38) | CNR2HSD11B1EPHX2 | |
| SCHEMBL3815509 | 0.85 | CNR2 (0.38) | CNR2CNR1 | |
| Methane SCHEMBL5656908 | 0.82 | CNR2 (0.45) | CNR2CNR1 | |
| SCHEMBL5660343 | 0.81 | MEN1 (0.42) | CNR2CNR1 | |
| SCHEMBL5657653 | 0.79 | CNR2 (0.42) | CNR2CNR1 | |
| SCHEMBL3815525 | 0.78 | CNR2 (0.62) | CNR2CNR1 | |
| SCHEMBL3820042 | 0.78 | CNR2 (0.62) | CNR2CNR1 | |
| SCHEMBL476601 | 0.77 | CNR2 (0.38) | CNR2CNR1 | |
| SCHEMBL3296756 | 0.77 | CNR2 (0.40) | CNR2CNR1 | |
| SCHEMBL476592 | 0.76 | CNR2 (0.56) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7202268-B2 | Derivatives of indole-3-carboxamide, preparation method thereof and application of same in therapeutics | SANOFI-AVENTIS (FR) | 2007-04-10 | — | — | US | disclosed |
| US-20050288356-A1 | Derivatives of indole-3-carboxamide, preparation method thereof and application of same in therapeutics | SANOFI-AVENTIS (FR) | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288356-A1 | Derivatives of indole-3-carboxamide, preparation method thereof and application of same in therapeutics | IDO1, IDO2, TDO2 | CNR2 4/4885CNR1 8/4885HSD11B1 1564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.