SCHEMBL2873174

SCHEMBL2873174

COC(=O)C(CSSCC(NC(C)=O)C(=O)OC)NC(C)=O

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ITGB1 P05556 2/20 0.48
ITGA4 P13612 2/20 0.48
KDM4E B2RXH2 1/20 0.41
MAPT P10636 1/20 0.41
THRB P10828 1/20 0.41
ALOX15 P16050 1/20 0.41
NFKB1 P19838 1/20 0.41
PTGS2 P35354 1/20 0.41
THPO P40225 1/20 0.41
RECQL P46063 1/20 0.41
BLM P54132 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ALDH1A1 P00352 2/20 0.39
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2872923 1.00 ITGB1 (0.48) ITGB1ITGA4KDM4EMAPTTHRB
SCHEMBL2408947 1.00 ITGB1 (0.48) ITGB1ITGA4KDM4EMAPTTHRB
SCHEMBL24378315 0.94 ITGB1 (0.44) ITGB1ITGA4KDM4EMAPTTHRB
SCHEMBL11774604 0.93 ITGB1 (0.57) ITGB1ITGA4KDM4EMAPTTHRB
SCHEMBL11774610 0.93 ITGB1 (0.57) ITGB1ITGA4KDM4EMAPTTHRB
SCHEMBL24359843 0.93 ITGB1 (0.57) ITGB1ITGA4KDM4EMAPTTHRB
SCHEMBL24374998 0.91 ITGB1 (0.43) ITGB1ITGA4KDM4EMAPTTHRB
SCHEMBL22764801 0.91 ITGB1 (0.43) ITGB1ITGA4KDM4EMAPTTHRB
SCHEMBL19216892 0.91 ITGB1 (0.43) ITGB1ITGA4KDM4EMAPTTHRB
SCHEMBL20839967 0.89 ITGB1 (0.42) ITGB1ITGA4KDM4EMAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240368072-A1 METHOD FOR PREPARATION OF N-ACETYL CYSTEINE AMIDE OR DI- N-ACETYL CYSTEINE AMIDE AND DERIVATIVES NACUITY PHARMACEUTICALS, INC. 2024-11-07 US claimed
US-20240342118-A1 METHOD FOR PREPARATION OF N-ACETYL CYSTEINE AMIDE OR DI- N-ACETYL CYSTEINE AMIDE AND DERIVATIVES NACUITY PHARMACEUTICALS, INC. 2024-10-17 US claimed
US-11859203-B2 Cell culture methods UCB Biopharma SRL (BE) 2024-01-02 US claimed
EP-3717631-B1 CELL CULTURE METHODS UCB Biopharma SRL (BE) 2023-08-30 EP claimed
US-20230159448-A1 Method for Preparation of N-Acetyl Cysteine Amide and Derivatives Thereof NACUITY PHARMACEUTICALS, INC. 2023-05-25 US claimed
US-11548851-B2 Method for preparation of n-acetyl cysteine amide and derivatives thereof NACUITY PHARMACEUTICALS, INC. (US) 2023-01-10 US claimed
US-20220024866-A1 Method for Preparation of N-Acetyl Cysteine Amide and Derivatives Thereof NACUITY PHARMACEUTICALS, INC. 2022-01-27 US claimed
US-11091433-B2 Method for preparation of N-acetyl cysteine amide and derivatives thereof Nacuity Pharmaceutials, Inc. (US) 2021-08-17 US claimed
EP-3717631-A1 CELL CULTURE METHODS UCB Biopharma SRL (BE) 2020-10-07 EP claimed
US-20200308536-A1 CELL CULTURE METHODS UCB PHARMA S.A. (BE) 2020-10-01 US claimed
US-10590073-B2 Method for preparation of N-acetyl cysteine amide and derivatives thereof NACUITY PHARMACEUTICALS, INC. (US) 2020-03-17 US claimed
EP-3492582-A1 CELL CULTURE METHODS UCB Biopharma SPRL (BE) 2019-06-05 EP claimed
WO-2019060623-A1 METHOD FOR PREPARATION OF N-ACETYL CYSTEINE AMIDE AND DERIVATIVES THEREOF NACUITY PHARMACEUTICALS, INC. (US) 2019-03-28 WO claimed
US-20190084926-A1 Method for Preparation of N-Acetyl Cysteine Amide and Derivatives Thereof NACUITY PHARMACEUTICALS, INC. 2019-03-21 US claimed
US-20080119551-A1 SKIN COSMETICS COMPRISING A CYSTINE DERIVATIVE AND A CHEMICAL PEELING AGENT, A BACTERICIDE, AN ANIONIC SUFACTANT, OR A CATIONIC SURFACTANT AJINOMOTO CO. INC (JP) 2008-05-22 US claimed
EP-0532595-B1 THE PHARMACOLOGICAL USE OF CERTAIN CYSTINE DERIVATIVES ASTRA AB (SE) 1996-10-30 EP claimed
EP-0727207-A1 The pharmacological use of certain cystine derivatives Astra Aktiebolag (SE) 1996-08-21 EP claimed
US-5441976-A Immunostimulants AKTIEBOLAGET ASTRA (SE) 1995-08-15 US claimed
EP-0532595-A1 THE PHARMACOLOGICAL USE OF CERTAIN CYSTINE DERIVATIVES. ASTRA AB (SE) 1993-03-24 EP claimed
WO-1991018594-A1 THE PHARMACOLOGICAL USE OF CERTAIN CYSTINE DERIVATIVES AKTIEBOLAGET ASTRA (SE) 1991-12-12 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11548851-B2 Method for preparation of n-acetyl cysteine amide and derivatives thereof AADAC, GCLC, DDC ITGB1 4098/4885ITGA4 3626/4885KDM4E 3352/4885
US-20220024866-A1 Method for Preparation of N-Acetyl Cysteine Amide and Derivatives Thereof AADAC, GCLC, DDC ITGB1 4098/4885ITGA4 3626/4885KDM4E 3352/4885
US-10590073-B2 Method for preparation of N-acetyl cysteine amide and derivatives thereof CTH, AHCY, AADAT ITGB1 4539/4885ITGA4 3215/4885KDM4E 3185/4885
US-20200308536-A1 CELL CULTURE METHODS CBS, CTH, SLC7A11 ITGB1 3908/4885ITGA4 3626/4885KDM4E 3920/4885
US-20190084926-A1 Method for Preparation of N-Acetyl Cysteine Amide and Derivatives Thereof CTH, AHCY, AADAT ITGB1 4539/4885ITGA4 3215/4885KDM4E 3185/4885
US-11091433-B2 Method for preparation of N-acetyl cysteine amide and derivatives thereof AADAC, GCLC, DDC ITGB1 4098/4885ITGA4 3626/4885KDM4E 3352/4885
US-20080119551-A1 SKIN COSMETICS COMPRISING A CYSTINE DERIVATIVE AND A CHEMICAL PEELING AGENT, A BACTERICIDE, AN ANIONIC SUFACTANT, OR A CATIONIC SURFACTANT CUTA, CTH, SRM ITGB1 4774/4885ITGA4 4745/4885KDM4E 2530/4885
US-11859203-B2 Cell culture methods CBS, CTH, SLC7A11 ITGB1 3908/4885ITGA4 3626/4885KDM4E 3920/4885
US-20230159448-A1 Method for Preparation of N-Acetyl Cysteine Amide and Derivatives Thereof AADAC, GCLC, DDC ITGB1 4330/4885ITGA4 3804/4885KDM4E 3674/4885
US-20240342118-A1 METHOD FOR PREPARATION OF N-ACETYL CYSTEINE AMIDE OR DI- N-ACETYL CYSTEINE AMIDE AND DERIVATIVES NAAA, AADAC, NAT1 ITGB1 3466/4885ITGA4 4069/4885KDM4E 4522/4885
US-20240368072-A1 METHOD FOR PREPARATION OF N-ACETYL CYSTEINE AMIDE OR DI- N-ACETYL CYSTEINE AMIDE AND DERIVATIVES NAAA, AADAC, NAT1 ITGB1 3466/4885ITGA4 4069/4885KDM4E 4522/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.