MGST3 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to MGST3 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Cysteine Supplementation in Critically Ill Neonates	PHASE2/PHASE3	UNKNOWN
Effect of Pioglitazone Administered to Patients With Friedreich's Ataxia: Proof of Concept	PHASE3	COMPLETED
EPI-743 in Cobalamin C Defect: Effects on Visual and Neurological Impairment	PHASE2	COMPLETED
Metabolic Cofactor Supplementation in Alzheimer's Disease (AD) and Parkinson's Disease (PD) Patients	PHASE2	COMPLETED
Effect of Melatonin in Patients With Diabetic Peripheral Neuropathy	PHASE2	RECRUITING
Metabolic Cofactor Supplementation in Obese Patients With Non-Alcoholic Fatty Liver Disease	PHASE2	COMPLETED
Clinical Trial of 2-HOBA in Pulmonary Arterial Hypertension	PHASE2	NOT_YET_RECRUITING
Efficacy and Tolerability of Tauroursodeoxycholic Acid in Amyotrophic Lateral Sclerosis	PHASE2	COMPLETED
N-Acetylcysteine for Neuroprotection in Parkinson's Disease	PHASE1/PHASE2	COMPLETED
Study of N-acetylcysteine in the Treatment of Patients With the m.3243A>G Mutation and Low Brain Glutathione Levels	PHASE1	RECRUITING
Tolerability of Enteral NAC in Infants	PHASE1	NOT_YET_RECRUITING
The Effects of a Glutathione Precursor (FT061452),on Serum and Intracellular Glutathione Levels	PHASE1	COMPLETED
Dynamics of Muscle Mitochondria in Type 2 Diabetes (DYNAMMO T2D)	EARLY_PHASE1	COMPLETED
MERC Proteins in Saliva and GCF in Periodontal Disease (ELISA Study)	nan	COMPLETED
Effect of Sulfur Amino Acid Depletion and Acetaminophen on Plasma Glutatione	nan	COMPLETED
Predicts Mortality by AST/ALT Ration in Patients with Sepsis and Septic Shock During ICU Admissin	nan	NOT_YET_RECRUITING
Thiol/Disulphide Homeostasis in Unexplained Infertility	nan	COMPLETED
Development of Biomarker for Development of Non-Alcoholic Steatohepatitis (NASH) in Children	nan	WITHDRAWN
The Natural History of Mitochondrial Diseases	nan	RECRUITING
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes	nan	COMPLETED
Dynamics of Muscle Mitochondria in Type 2 Diabetes Exercise	nan	COMPLETED
Evaluation of Mitochondrial Enzyme Activity in Cesarean Section Patients	nan	UNKNOWN
Cell Signaling and Resistance to Oxidative Stress: Effects of Aging and Exercise	nan	COMPLETED
Tissue Sample Study for Mitochondrial Disorders	nan	ENROLLING_BY_INVITATION
Measuring Protein Turnover in Humans Across the Lifespan by Metabolic Labeling With Deuterium Oxide	nan	RECRUITING
ADAPT: Efficacy of a Dietary Supplement During and After Exercise	nan	COMPLETED
Clinical Study of Hydroxytyrosol (HT) in Mitochondrial Diseases	nan	COMPLETED
Mitochondrial Function of Immune Cells in Sepsis	nan	COMPLETED
Relationship Between Fatigue and Mitochondrial Damage in Patients With HIV/AIDS	nan	COMPLETED
Effect of Protein on Endoplasmic Reticulum Stress	nan	NOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a MGST3 binder may also engage these)

Protein	Name	Similarity
Q9CPU4	—	1.000	Q9CPU4 →
Q3T100	—	0.996	Q3T100 →
Q99735	—	0.982	Q99735 →
Q64L89	—	0.975	Q64L89 →
MGST1	Microsomal glutathione S-transferase 1	0.974	landscape →
Q91VS7	—	0.974	Q91VS7 →
Q2KJG4	—	0.972	Q2KJG4 →
P79382	—	0.972	P79382 →
P08011	—	0.971	P08011 →
Q9JHF3	—	0.970	Q9JHF3 →
Q9JM51	—	0.968	Q9JM51 →
A2RST1	—	0.967	A2RST1 →
PTGES	Prostaglandin E synthase	0.967	landscape →
Q6PWL6	—	0.966	Q6PWL6 →
A0SYQ0	—	0.963	A0SYQ0 →
Q8HZJ2	—	0.963	Q8HZJ2 →
Q95L14	—	0.963	Q95L14 →
P31214	—	0.961	P31214 →
Q99N99	—	0.960	Q99N99 →
Q9D3B1	—	0.959	Q9D3B1 →
Q9N5Y2	—	0.959	Q9N5Y2 →
Q28892	—	0.959	Q28892 →
Q5RBK3	—	0.958	Q5RBK3 →
Q2KIP8	—	0.957	Q2KIP8 →
Q55C17	—	0.957	Q55C17 →
P70245	—	0.957	P70245 →
HACD2	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2	0.956	landscape →
O18765	—	0.956	O18765 →
Q7ZXH1	—	0.955	Q7ZXH1 →
Q5R7H4	—	0.955	Q5R7H4 →