SCHEMBL565709

SCHEMBL565709

CCc1c(N)c(N)c(S(=O)(=O)O)c2ccccc12

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAPK1 P53355 1/20 0.36
TTR P02766 1/20 0.35
SENP2 Q9HC62 4/20 0.35
SENP1 Q9P0U3 4/20 0.35
SUMO2 P61956 3/20 0.35
SUMO1 P63165 3/20 0.35
SENP7 Q9BQF6 3/20 0.35
SENP3 Q9H4L4 2/20 0.35
SLC2A1 P11166 1/20 0.33
CYP2D6 P10635 1/20 0.33
TDP1 Q9NUW8 2/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
APP P05067 1/20 0.32
MAPT P10636 1/20 0.32
THRB P10828 1/20 0.32
HPGD P15428 1/20 0.32
ALOX12 P18054 1/20 0.32
SNCA P37840 1/20 0.32
RECQL P46063 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2521849 0.81 CYP2D6 (0.35) TTRSLC2A1CYP2D6TDP1MEN1
SCHEMBL2521780 0.81 CYP2D6 (0.35) SLC2A1CYP2D6TDP1MEN1ALDH1A1
Formaldehyde SCHEMBL19137779 0.78 SLC2A1 (0.33) SLC2A1CYP2D6TDP1MEN1ALDH1A1
SCHEMBL9401963 0.76 DAPK1 (0.43) DAPK1TTRSENP2SENP1SUMO2
SCHEMBL28551848 0.75 HTT (0.36) CYP2D6TDP1ALDH1A1MAPTHPGD
SCHEMBL7779121 0.75 KDM4E (0.41) SLC2A1CYP2D6ALDH1A1HPGDHTT
SCHEMBL1244463 0.74 DAPK1 (0.42) DAPK1TTRSENP2SENP1SUMO2
SCHEMBL6526692 0.74 DAPK1 (0.42) DAPK1TTRSENP2SENP1SUMO2
SCHEMBL31552425 0.74 DAPK1 (0.42) DAPK1TTRSENP2SENP1SUMO2
SCHEMBL8576283 0.74 SENP2 (0.40) DAPK1TTRSENP2SENP1SUMO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1802710-B1 METHODS FOR FORMING DYED MICROSPHERES AND POPULATIONS OF DYED MICROSPHERES LUMINEX CORP (US) 2016-02-24 EP disclosed
EP-2559738-B1 Methods for forming dyed microspheres and populations of dyed microspheres LUMINEX CORP (US) 2014-07-09 EP disclosed
EP-2559738-A1 Methods for forming dyed microspheres and populations of dyed microspheres Luminex Corporation (US) 2013-02-20 EP disclosed
US-8361169-B2 Methods for forming dyed microspheres and populations of dyed microspheres LUMINEX CORPORATION (US) 2013-01-29 US disclosed
US-20120035328-A1 METHODS FOR FORMING DYED MICROSPHERES AND POPULATIONS OF DYED MICROSPHERES HOFFACKER KURT D (US) 2012-02-09 US disclosed
US-8038734-B2 Methods for forming dyed microspheres and populations of dyed microspheres LUMINEX CORPORATION (US) 2011-10-18 US disclosed
US-20060085925-A1 Methods for forming dyed microspheres and populations of dyed microspheres LUMINEX CORPORATION 2006-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120035328-A1 METHODS FOR FORMING DYED MICROSPHERES AND POPULATIONS OF DYED MICROSPHERES CD68, CD14, MYADM DAPK1 2452/4885TTR 3570/4885SENP2 2492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.