Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852219 | 0.87 | L3MBTL1 (0.65) | L3MBTL1PAOXLMNAMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7430675 | 0.85 | L3MBTL1 (0.63) | L3MBTL1PAOXLMNAMAPTSMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL29413588 | 0.84 | KDM4E (0.44) | PAOXTSHRALDH1A1POLB | |
| Trifluoroacetic Acid SCHEMBL3749224 | 0.81 | GLA (0.56) | L3MBTL1LMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL31008699 | 0.80 | L3MBTL1 (0.68) | L3MBTL1PAOXMAPTSMN1; SMN2TP53 | |
| Trifluoroacetic Acid SCHEMBL23292174 | 0.79 | CYP1A2 (0.46) | L3MBTL1LMNAMAPTTSHRALDH1A1 | |
| SCHEMBL8860545 | 0.79 | L3MBTL1 (0.77) | L3MBTL1PAOXMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11598668 | 0.79 | L3MBTL1 (0.77) | L3MBTL1PAOXMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL2091283 | 0.77 | PAOX (0.60) | L3MBTL1PAOXLMNASMN1; SMN2TP53 | |
| Trifluoroacetic Acid SCHEMBL4700418 | 0.77 | L3MBTL1 (0.58) | L3MBTL1MAPTSMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7309701-B2 | Pyridazinone derivatives as pharmaceuticals and pharmaceutical compositions containing them | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-12-18 | — | — | US | disclosed |