Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 3/20 | 0.52 |
| ▸ | DRD2 | P14416 | 5/20 | 0.50 |
| ▸ | DRD3 | P35462 | 4/20 | 0.50 |
| ▸ | HTR6 | P50406 | 3/20 | 0.50 |
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | HTR2C | P28335 | 3/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL566352 | 0.91 | MLNR (0.61) | MLNRDRD2DRD3HTR6HTR2A | |
| SCHEMBL18774013 | 0.87 | PLAU (0.55) | MLNRDRD2DRD3HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL565965 | 0.86 | DRD2 (0.51) | DRD2DRD3HTR6HTR2AHTR2C | |
| SCHEMBL19996369 | 0.82 | SLC6A2 (0.50) | MLNRDRD2HTR2AHTR2CS1PR1 | |
| SCHEMBL9747402 | 0.80 | S1PR1 (0.49) | MLNRDRD2HTR2AHTR2CS1PR1 | |
| SCHEMBL8776566 | 0.80 | S1PR1 (0.49) | MLNRDRD2HTR2AHTR2CS1PR1 | |
| SCHEMBL31083766 | 0.80 | ASIC3 (0.55) | DRD2DRD3PLAUASIC3 | |
| SCHEMBL1696305 | 0.80 | ASIC3 (0.55) | DRD2DRD3PLAUASIC3 | |
| SCHEMBL15312357 | 0.79 | S1PR1 (0.48) | MLNRDRD2HTR2AHTR2CS1PR1 | |
| SCHEMBL28830783 | 0.79 | S1PR1 (0.47) | MLNRDRD2HTR2AHTR2CS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181182-B2 | S1P receptors modulators | AKAAL PHARMA PTY LTD (AU) | 2015-11-10 | — | — | US | disclosed |
| US-20120034270-A1 | S1P Receptors Modulators | AKAAL PHARMA PTY LTD (AU) | 2012-02-09 | — | — | US | disclosed |
| EP-2344446-A1 | S1P RECEPTORS MODULATORS | Akaal Pharma Pty Ltd (AU) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010042998-A1 | S1P RECEPTORS MODULATORS | AKAAL PHARMA PTY LTD (AU) | 2010-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120034270-A1 | S1P Receptors Modulators | S1PR1, S1PR5, S1PR3 | MLNR 1335/4885DRD2 1786/4885DRD3 2302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.