Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | FOS | P01100 | 1/20 | 0.42 |
| ▸ | JUN | P05412 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28134004 | 0.94 | NPC1 (0.56) | NPC1POLBLMNAKMT2ACYP1A2 | |
| SCHEMBL28134795 | 0.91 | HTT (0.59) | NPC1POLBLMNACYP1A2CYP2C19 | |
| SCHEMBL28134782 | 0.85 | HTT (0.58) | NPC1POLBLMNAHTTMAPT | |
| SCHEMBL28133971 | 0.81 | LMNA (0.49) | POLBLMNAHTTNPSR1ALDH1A1 | |
| SCHEMBL5655185 | 0.81 | TUBB4A (0.44) | NPC1POLBLMNARAB9AHTT | |
| SCHEMBL490637 | 0.78 | POLB (0.71) | NPC1POLBCYP1A2CYP2C19PKM | |
| SCHEMBL9321551 | 0.77 | NPC1 (0.57) | NPC1POLBLMNAKMT2ACYP1A2 | |
| SCHEMBL12228745 | 0.76 | NPC1 (0.68) | NPC1POLBLMNAKMT2ACYP1A2 | |
| SCHEMBL2968686 | 0.76 | NPC1 (0.60) | NPC1POLBLMNAKMT2ACYP1A2 | |
| SCHEMBL3182853 | 0.76 | NPC1 (0.68) | NPC1POLBLMNAKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101842101-A | Salicylanilide modified peptides for use as oral therapeutics | UNIV CALIFORNINA | 2010-09-22 | — | — | CN | disclosed |
| CN-101522207-A | Salicylanilides enhance oral delivery of therapeutic peptides | UNIV CALIFORNINA (US) | 2009-09-02 | — | — | CN | disclosed |
| US-7071214-B2 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2006-07-04 | — | — | US | disclosed |