Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTBP2 | P56545 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | AGXT | P21549 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1326762 | 0.89 | CTBP2 (0.60) | CTBP2CYP1A2MAPK8MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL13727108 | 0.88 | CTBP2 (0.59) | CTBP2CYP1A2MAPK8MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL5655817 | 0.82 | HTT (0.51) | CTBP2 | |
| 1,3-Dimethoxybenzene SCHEMBL11452224 | 0.81 | LMNA (0.58) | MEN1KMT2APARP1KDM4E | |
| SCHEMBL3837938 | 0.81 | MAOB (0.51) | CTBP2MAPK8USP2IDO1AGXT | |
| Trifluoroacetic Acid SCHEMBL4222769 | 0.81 | CTBP2 (0.51) | CTBP2CYP1A2MAPK8GRM2GRM3 | |
| Trifluoroacetic Acid SCHEMBL6424557 | 0.79 | LDHA (0.53) | CYP1A2MEN1KMT2ACTSDKDM4E | |
| Trifluoroacetic Acid SCHEMBL5657379 | 0.79 | CTBP2 (0.50) | CTBP2CYP1A2KMT2AGRM2GRM3 | |
| Trifluoroacetic Acid SCHEMBL5660867 | 0.79 | SLC1A1 (0.47) | CYP1A2MAPK8PARP1TAAR1 | |
| SCHEMBL6685564 | 0.79 | EPHX1 (0.52) | GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7309701-B2 | Pyridazinone derivatives as pharmaceuticals and pharmaceutical compositions containing them | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-12-18 | — | — | US | disclosed |