Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 15/20 | 0.57 |
| ▸ | CXCR1 | P25024 | 14/20 | 0.57 |
| ▸ | KLK7 | P49862 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5659864 | 0.96 | CXCR2 (0.54) | CXCR2CXCR1KLK7P4HTM | |
| SCHEMBL5846560 | 0.88 | CXCR1 (0.73) | CXCR2CXCR1 | |
| SCHEMBL5660642 | 0.84 | CXCR2 (0.75) | CXCR2CXCR1P4HTM | |
| SCHEMBL5845104 | 0.83 | CXCR1 (0.73) | CXCR2CXCR1P4HTM | |
| SCHEMBL5658521 | 0.83 | CXCR2 (0.77) | CXCR2CXCR1P4HTM | |
| SCHEMBL5658866 | 0.83 | CXCR2 (0.77) | CXCR2CXCR1P4HTM | |
| SCHEMBL5656391 | 0.82 | CXCR1 (0.75) | CXCR2CXCR1P4HTM | |
| SCHEMBL5659934 | 0.82 | CXCR2 (0.61) | CXCR2CXCR1 | |
| SCHEMBL5658349 | 0.81 | CXCR2 (0.73) | CXCR2CXCR1P4HTM | |
| SCHEMBL5661579 | 0.79 | CXCR2 (0.57) | CXCR2CXCR1P4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176310-B1 | Pyrimidinecarboxamide derivatives and their use as anti-inflammatory agents | UCB SA (GB) | 2007-02-13 | — | — | US | disclosed |