Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTBP2 | P56545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CHIT1 | Q13231 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | GNRHR | P30968 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29718576 | 0.88 | CTBP2 (0.55) | CTBP2ALDH1A1GAAMAPK8KDM4E | |
| SCHEMBL158861 | 0.88 | CTBP2 (0.55) | CTBP2ALDH1A1GAAMAPK8KDM4E | |
| Hydrochloric Acid SCHEMBL14167478 | 0.86 | CTBP2 (0.53) | CTBP2ALDH1A1GAAMAPK8KDM4E | |
| Trifluoroacetic Acid SCHEMBL5657301 | 0.81 | ALDH1A1 (0.46) | ALDH1A1MAPK8CHIT1KMT2AMEN1 | |
| Trifluoroacetic Acid SCHEMBL5658062 | 0.80 | PKM (0.51) | CTBP2MAPK8 | |
| Trifluoroacetic Acid SCHEMBL5076869 | 0.80 | SMN1; SMN2 (0.53) | MAPK8KDM4ETDP1CHIT1KMT2A | |
| SCHEMBL28757860 | 0.79 | CES1 (0.55) | CTBP2ALDH1A1GAAMAPK8KDM4E | |
| Trifluoroacetic Acid SCHEMBL27625600 | 0.79 | KMT2A (0.47) | KMT2ACES1FFAR1 | |
| Trifluoroacetic Acid SCHEMBL29921868 | 0.78 | TDP1 (0.60) | MAPK8KDM4EATMTDP1HPGD | |
| Trifluoroacetic Acid SCHEMBL5892868 | 0.77 | CES1 (0.62) | KMT2AMEN1CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7309701-B2 | Pyridazinone derivatives as pharmaceuticals and pharmaceutical compositions containing them | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-12-18 | — | — | US | disclosed |