Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 12/20 | 0.55 |
| ▸ | HRH1 | P35367 | 11/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2912611 | 0.86 | HRH1 (0.74) | CCR3HRH1KCNH2 | |
| SCHEMBL5655573 | 0.84 | CCR3 (0.66) | CCR3HRH1KCNH2 | |
| SCHEMBL5656798 | 0.84 | CCR3 (0.53) | CCR3HRH1KCNH2EPHX2 | |
| SCHEMBL5660256 | 0.82 | CCR3 (0.55) | CCR3HRH1KCNH2EPHX2 | |
| SCHEMBL18841165 | 0.74 | HRH1 (0.78) | CCR3HRH1KCNH2ALDH1A1 | |
| SCHEMBL18841149 | 0.74 | HRH1 (0.78) | CCR3HRH1KCNH2ALDH1A1 | |
| SCHEMBL3281914 | 0.73 | HRH1 (0.85) | CCR3HRH1KCNH2 | |
| SCHEMBL3283057 | 0.73 | HRH1 (0.85) | CCR3HRH1KCNH2 | |
| SCHEMBL6398901 | 0.72 | CCR3 (0.68) | CCR3HRH1KCNH2 | |
| Hydrochloric Acid SCHEMBL5657160 | 0.72 | CCR3 (0.62) | CCR3HRH1KCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7304077-B2 | Chemical compounds | ASTRAZENECA AB (SE) | 2007-12-04 | — | — | US | disclosed |
| US-20040102432-A1 | Chemical compounds | ASTRAZENECA AB (SE) | 2004-05-27 | — | — | US | disclosed |
| EP-1322611-A1 | CHEMICAL COMPOUNDS | AstraZeneca AB (SE) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002020484-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2002-03-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102432-A1 | Chemical compounds | CCL11, HRH1, HRH4 | CCR3 17/4885HRH1 2/4885KCNH2 1645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.