Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 10/20 | 0.53 |
| ▸ | HRH1 | P35367 | 9/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5658272 | 0.84 | CCR3 (0.55) | CCR3HRH1KCNH2EPHX2 | |
| SCHEMBL5656532 | 0.84 | CCR3 (0.59) | CCR3HRH1KCNH2SLC5A7HRH3 | |
| SCHEMBL5658546 | 0.83 | CCR3 (0.68) | CCR3HRH1KCNH2HRH3CCR2 | |
| SCHEMBL5660256 | 0.83 | CCR3 (0.55) | CCR3HRH1KCNH2SLC5A7HRH3 | |
| SCHEMBL13176904 | 0.78 | CCR3 (0.61) | CCR3HRH1KCNH2HRH3DRD2 | |
| SCHEMBL18841165 | 0.77 | HRH1 (0.78) | CCR3HRH1KCNH2 | |
| SCHEMBL18841149 | 0.77 | HRH1 (0.78) | CCR3HRH1KCNH2 | |
| SCHEMBL180485 | 0.77 | CCR3 (0.80) | CCR3HRH1KCNH2HRH3 | |
| SCHEMBL5658388 | 0.76 | CCR3 (0.53) | CCR3HRH1KCNH2SLC5A7 | |
| Hydrochloric Acid SCHEMBL5656041 | 0.73 | CCR3 (0.75) | CCR3HRH1KCNH2SLC5A7HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7304077-B2 | Chemical compounds | ASTRAZENECA AB (SE) | 2007-12-04 | — | — | US | disclosed |
| US-20040102432-A1 | Chemical compounds | ASTRAZENECA AB (SE) | 2004-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102432-A1 | Chemical compounds | CCL11, HRH1, HRH4 | CCR3 17/4885HRH1 2/4885KCNH2 1645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.