SCHEMBL5658338

SCHEMBL5658338

c1ccc2c(c1)c1ccccc1n2CCCCCCCCCCn1c2ccccc2c2ccccc21

nearest known ligand 0.69

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAOA P21397 10/20 0.69
MAOB P27338 10/20 0.69
ACHE P22303 3/20 0.69
FABP4 P15090 2/20 0.66
FABP5 Q01469 2/20 0.66
GRIN1 Q05586 8/20 0.65
GRIN2A Q12879 8/20 0.65
GRIN2B Q13224 8/20 0.65
HDAC1 Q13547 3/20 0.62
HDAC6 Q9UBN7 3/20 0.62
CYP1A2 P05177 1/20 0.61
CYP2C19 P33261 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10063551 1.00 MAOA (0.69) MAOAMAOBACHEFABP4FABP5
SCHEMBL6338101 1.00 MAOA (0.69) MAOAMAOBACHEFABP4FABP5
SCHEMBL5181736 1.00 MAOA (0.69) MAOAMAOBACHEFABP4FABP5
SCHEMBL4552481 0.97 FABP4 (0.68) MAOAMAOBACHEFABP4FABP5
SCHEMBL4552166 0.92 FABP4 (0.64) MAOAMAOBACHEFABP4FABP5
SCHEMBL25354476 0.89 MAOA (0.59) MAOAMAOBACHEFABP4FABP5
SCHEMBL24398894 0.89 FABP4 (0.61) MAOAMAOBACHEFABP4FABP5
SCHEMBL4203950 0.89 MAOA (0.59) MAOAMAOBACHEFABP4FABP5
SCHEMBL24293943 0.89 MAOA (0.59) MAOAMAOBACHEFABP4FABP5
SCHEMBL3066305 0.89 FABP4 (0.61) MAOAMAOBACHEFABP4FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130128339-A1 PHOTOREFRACTIVE COMPOSITION RESPONSIVE TO MULTIPLE LASER WAVELENGTHS ACROSS THE VISIBLE LIGHT SPECTRUM NITTO DENKO CORPORATION (JP) 2013-05-23 US disclosed
US-7202004-B2 Charge transport compound containing at least two carbazolecarboxaldehyde substituted- hydrazone groups SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-04-10 US disclosed
US-7118839-B2 Electrophotographic organophotoreceptors with novel charge transport materials SAMSUNG ELECTRONICS CO., LTD. (KR) 2006-10-10 US disclosed
US-20050058917-A1 Electrophotographic organophotoreceptors with novel charge transport materials SAMSUNG ELECTRONICS CO., LTD. 2005-03-17 US disclosed
US-20030113643-A1 Electrophotographic organophotoreceptors with novel charge transport materials SAMSUNG ELECTRONICS CO. LTD. 2003-06-19 US disclosed
EP-1298496-A2 Electrophotographic organophotoreceptors SAMSUNG ELECTRONICS Co. Ltd. (KR) 2003-04-02 EP disclosed
US-6140004-A LAMINATION A SUBSTRATE AND CHARGE TRANSPORT LAYER IMATION CORP. (US) 2000-10-31 US disclosed
US-6066426-A ORGANIC PHOTORECEPTOR COMPRISING ARYLHYDRAZONE OF 3-FORMYL CARBAZOLE AS CHARGE TRANSPORT COMPOUND IMATION CORP. (US) 2000-05-23 US disclosed
WO-2000022483-A1 ORGANIC PHOTORECEPTORS FOR ELECTROPHOTOGRAPHY CONTAINING HYDRAZONE CHARGE TRANSPORT COMPOUNDS IMATION CORP. (US) 2000-04-20 WO disclosed