Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.53 |
| ▸ | SUV39H2 | Q9H5I1 | 6/20 | 0.49 |
| ▸ | CKS1B | P61024 | 1/20 | 0.48 |
| ▸ | SKP1 | P63208 | 1/20 | 0.48 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.48 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3073225 | 0.95 | CHRNB2 (0.57) | CHRNB2CHRNA4SUV39H2ALKGPR119 | |
| SCHEMBL6351591 | 0.90 | CHRNB2 (0.55) | CHRNB2CHRNA4SUV39H2CKS1BSKP1 | |
| SCHEMBL5658366 | 0.89 | CKS1B (0.50) | SUV39H2CKS1BSKP1SKP2GPR119 | |
| SCHEMBL5657135 | 0.89 | CHRNB2 (0.57) | CHRNB2CHRNA4SUV39H2CKS1BSKP1 | |
| SCHEMBL5655638 | 0.89 | CKS1B (0.47) | CHRNB2CHRNA4SUV39H2CKS1BSKP1 | |
| SCHEMBL6351766 | 0.88 | CHRNB2 (0.54) | CHRNB2CHRNA4SUV39H2CKS1BSKP1 | |
| SCHEMBL5658601 | 0.87 | CHRNB2 (0.49) | CHRNB2CHRNA4SUV39H2CKS1BSKP1 | |
| SCHEMBL25192257 | 0.83 | ALK (0.50) | SUV39H2ALKGPR119MAPTALDH1A1 | |
| SCHEMBL31173935 | 0.83 | ALK (0.50) | SUV39H2ALKGPR119MAPTALDH1A1 | |
| SCHEMBL5657487 | 0.82 | CHRNB2 (0.49) | CHRNB2CHRNA4SUV39H2CKS1BSKP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7282494-B2 | Heteroaryl diazacycloalkanes, their preparation and use | NEUROSEARCH A/S (DK) | 2007-10-16 | — | — | US | disclosed |
| US-7064118-B2 | Heteroaryl diazacycloalkanes, their preparation and use | NEUROSEARCH A/S (DK) | 2006-06-20 | — | — | US | disclosed |
| US-20060100192-A1 | Heteroaryl diazacycloalkanes, their preparation and use | DANPET AB (SE) | 2006-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100192-A1 | Heteroaryl diazacycloalkanes, their preparation and use | CHRNA5, CHRNA7, CHRNA3 | CHRNB2 10/4885CHRNA4 9/4885SUV39H2 1661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.